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Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127300Source: DataRank Database

Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers is a research paper published in Bioorganic & Medicinal Chemistry Letters (2020). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (5 grants)Impact (FWCI 0.37)OA: greenTopics (56)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Zhiqing Liu ORCID,Galina V. Aglyamova ORCID,Jianping Chen ORCID,Haiying Chen ORCID,Mukund Bhandari ORCID

Live enrichment

PubMed:32631520 PMC:PMC7376976 OpenAlex:https://openalex.org/W3033818658

NIDA NIH HHS

Grant: R01 DA040621

National Institutes of Health

Grant: 2R01DA040621-06

Small molecule modulators of ΔFosB

Michigan State University

Texas A&M University

Icahn School of Medicine at Mount Sinai

FWCI

0.37

Citation Percentile

0.6%

Citation Trend

2021

2022

2023

2025

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7376976

GREENhttps://www.ncbi.nlm.nih.gov/pmc/articles/7376976

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7376976

publisherhttps://api.elsevier.com/content/article/PII:S0960894X2030411X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0960894X2030411X?httpAccept=text/plain

Fields of Study

Epigenetics and DNA MethylationDNA and Nucleic Acid ChemistryGenomics and Chromatin DynamicsMedicineChemistry0301 basic medicine0303 health sciences03 medical and health sciencesBinding SitesDNADose-Response Relationship, DrugDrug DiscoveryHumansMolecular Docking SimulationMolecular StructurePhenanthridinesProto-Oncogene Proteins c-fosProto-Oncogene Proteins c-junStructure-Activity Relationship

MeSH Terms

Binding SitesDNADose-Response Relationship, DrugHumansPhenanthridinesStructure-Activity RelationshipMolecular StructureProto-Oncogene Proteins c-junProto-Oncogene Proteins c-fosDrug DiscoveryMolecular Docking Simulation

Keywords

FOSBChemistryPhenanthridineTranscription factorSmall moleculePharmacologyStereochemistryBiochemistryGeneBiologyHigh-throughput screeningChemical ProbesFluorescence Polarization AssayΔfosb HomodimerΔfosb/jund HeterodimerBinding SitesDose-Response Relationship, DrugMolecular StructureProto-Oncogene Proteins c-junDNAPhenanthridinesMolecular Docking SimulationStructure-Activity RelationshipDrug DiscoveryHumansProto-Oncogene Proteins c-fos

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers

FAIR Checklist

Authors (9)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)