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Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an 11C-labeled radiotracer in rodents

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127573Source: DataRank Database

Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an 11C-labeled radiotracer in rodents is a research paper published in Bioorganic & Medicinal Chemistry Letters (2020). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (15 grants)Impact (FWCI 0.00)OA: greenTopics (59)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Lixia Du ORCID,Qianwa Liang ORCID,Hongzhen Hu ORCID,Zhude Tu ORCID,Lin Qiu ORCID

Live enrichment

PubMed:32980513 PMC:PMC8627648 OpenAlex:https://openalex.org/W3089249760

National Institutes of Health

Grant: R01AA027065

National Institutes of Health

Grant: R01DK103901

National Institute on Aging

Grant: NS103957

National Institute on Aging

Grant: NS075527

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: P30 DK052574

NINDS NIH HHS

Grant: R01 NS107281

NIAMS NIH HHS

Grant: R01 AR077183

NINDS NIH HHS

Grant: R01 NS075527

NINDS NIH HHS

Grant: R01 NS103957

National Institutes of Health

Grant: 1P30DK052574-01A1

Core--Transgenic mouse and stem cell

National Institutes of Health

Grant: 1R01AA027065-01

MECHANISMS OF TRPV4-MEDIATED NEUROPATHIC PAIN

National Institutes of Health

Grant: 5R01DK103901-03

TARGETING THE TRANSIENT RECEPTOR POTENTIAL CHANNELS TO IMPROVE BOWEL DYSFUNCTION

National Institutes of Health

USA

National Institute of Neurological Disorders and Stroke

FWCI

0.00

Citation Percentile

0.1%

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8627648

publisherhttps://api.elsevier.com/content/article/PII:S0960894X20306843?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0960894X20306843?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmcl.2020.127573

Fields of Study

Ion Channels and ReceptorsPhytochemicals and Antioxidant ActivitiesBiochemical Analysis and Sensing Techniques0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsCalciumCarbon RadioisotopesDose-Response Relationship, DrugLigandsMiceMolecular StructureRadioactive TracersRadiopharmaceuticalsStructure-Activity RelationshipTRPV Cation ChannelsTissue Distribution

MeSH Terms

AnimalsCalciumCarbon RadioisotopesDose-Response Relationship, DrugLigandsRadioactive TracersStructure-Activity RelationshipTissue DistributionMolecular StructureRadiopharmaceuticalsTRPV Cation ChannelsMice

Keywords

RadiosynthesisChemistryBiodistributionRadiochemistryIn vivoIn vitroAgonistChemical synthesisEx vivoNuclear chemistryMethyl iodideBiochemistryReceptorMedicinal chemistryAnaloguesPETTrpv4Dose-Response Relationship, DrugMolecular StructureTRPV Cation ChannelsLigandsMiceStructure-Activity RelationshipAnimalsCalciumTissue DistributionCarbon RadioisotopesRadioactive TracersRadiopharmaceuticals

Sustainable Development Goals

SDG 3: 3. Good health