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Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y6 receptor antagonists

Bioorganic & Medicinal Chemistry Letters(2022)10.1016/j.bmcl.2022.128981Source: DataRank Database

Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y6 receptor antagonists is a research paper published in Bioorganic & Medicinal Chemistry Letters (2022). On theSindex it has a DataRank of 0. It has been cited 18 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access18 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 1.99)OA: greenTopics (36)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Qasim Shah ORCID,Sarah A. Lewicki ORCID,Asmita Pramanik,Varun Gopinatth ORCID,Julie Pelletier ORCID

Live enrichment

PubMed:36089113 PMC:PMC9555146 OpenAlex:https://openalex.org/W4294957697

NIDDK

Grant: ZIADK31116

Crohn's and Colitis Canada

Grant: FO131330

Crohn's and Colitis Canada

Grant: HHSN-271-2008-00025-C

Intramural NIH HHS

Grant: ZIA DK031116

Intramural NIH HHS

Grant: Z01 DK031116

NIMH NIH HHS

Grant: HHSN271200800025C

FWCI

1.99

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9555146

publisherhttps://api.elsevier.com/content/article/PII:S0960894X22004577?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0960894X22004577?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmcl.2022.128981

Fields of Study

Adenosine and Purinergic SignalingPharmacological Receptor Mechanisms and EffectsReceptor Mechanisms and SignalingAnimalsBenzopyransHalogensHumansMiceReceptors, Purinergic P2Structure-Activity RelationshipUridine Diphosphate

MeSH Terms

AnimalsBenzopyransHalogensHumansStructure-Activity RelationshipUridine DiphosphateReceptors, Purinergic P2Mice

Keywords

ChemistryStereochemistryChemical synthesisIn vivoAgonistStructure–activity relationshipReceptorTrifluoromethylIC50PharmacologyIn vitroBiochemistryAntagonistStructure activity relationshipPurinergicCalcium MobilizationP2y Receptor

Sustainable Development Goals

SDG 0: Good health and well-being