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Structure-activity of Bastadins from the marine sponge Ianthella basta. Modulators of the RYR1 Ca2+ channel

Bioorganic & Medicinal Chemistry Letters(2025)10.1016/j.bmcl.2025.130165Source: DataRank Database

Structure-activity of Bastadins from the marine sponge Ianthella basta. Modulators of the RYR1 Ca2+ channel is a research paper published in Bioorganic & Medicinal Chemistry Letters (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 0.00)OA: closedTopics (29)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Mariam N. Salib ORCID,Juliette Gafni,Isaac N. Pessah ORCID,Tadeusz F. Molinski ORCID,Melanie A. Franklin

Live enrichment

PubMed:40043821 OpenAlex:https://openalex.org/W4408098550

National Institutes of Health

Grant: R/MP-57

National Institutes of Health

Grant: S10RR025636

National Institutes of Health

Grant: GM57560

National Institutes of Health

Grant: ES11269

National Science Foundation

Grant: CHE0741968

University of California, San Diego

National Stroke Foundation

Carl von Ossietzky Universität Oldenburg

FWCI

0.00

Citation Percentile

0.0%

closedLicense: https://doi.org/10.15223/policy-004

publisherhttps://api.elsevier.com/content/article/PII:S0960894X25000745?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0960894X25000745?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmcl.2025.130165

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40043821

Fields of Study

Marine Sponges and Natural ProductsSynthesis and Catalytic ReactionsEnzyme function and inhibitionAnimalsStructure-Activity RelationshipRyanodine Receptor Calcium Release ChannelPoriferaHumansMolecular StructureDose-Response Relationship, Drug

MeSH Terms

AnimalsDose-Response Relationship, DrugHumansPoriferaStructure-Activity RelationshipMolecular StructureRyanodine Receptor Calcium Release Channel

Keywords

ChemistrySpongePharmacognosyStereochemistryBiological activityIn vitroBotanyBiochemistrySynthesisAlkaloidMarine Natural ProductCa(2+) Channel

Sustainable Development Goals

SDG 0: Life below water

Structure-activity of Bastadins from the marine sponge Ianthella basta. Modulators of the RYR1 Ca2+ channel

FAIR Checklist

Authors (5)

Funding (8 grants)

Impact

Open Access

Topics