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Reduction in [18F]Nifene Binding, a PET imaging Probe for α4β2* Nicotinic acetylcholinergic receptors in Hippocampus-Subiculum of postmortem human Alzheimer’s disease brain

Brain Research(2025)10.1016/j.brainres.2025.149600Source: DataRank Database

Reduction in [18F]Nifene Binding, a PET imaging Probe for α4β2* Nicotinic acetylcholinergic receptors in Hippocampus-Subiculum of postmortem human Alzheimer’s disease brain is a research paper published in Brain Research (2025). On theSindex it has a DataRank of 0.276. It has been cited 5 times, with 1 citing works in its 1-hop citation network.

N/A

0.276DataRank · unranked

Scored on demand from live citation data

Open Access5 citations · 1 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (22 grants)Impact (FWCI 2.34)OA: hybridTopics (73)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 97%Citation Network 3%

Base Score Contribution

0.269

From this paper's citation signal

Citation Network Contribution

7.02 × 10⁻³

From 1 citing papers with measurable signal

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Top 1 citer driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 1 citer.

Harmine and its derivatives: A promising multi-target therapeutic avenue for Alzheimer’s disease
Neuroscience20262 citations133 referencesContributes 0.008

Authors (8)

Ambrose Loc T Ngo ORCID,Tram B. Danh,Brooke A. Delaney,Christopher Liang ORCID,Geidy E. Serrano ORCID

Live enrichment

PubMed:40154862 PMC:PMC12245395 OpenAlex:https://openalex.org/W4408932047

National Institute on Aging

Grant: AG 079189

National Institute on Aging

Grant: AG 029479

National Institute on Aging

Grant: AG 077700

Arizona Department of Health Services

Grant: 211002

National Institute of Neurological Disorders and Stroke

Grant: U24 NS072026

National Institute of Neurological Disorders and Stroke

Grant: P30 AG19610

Arizona Biomedical Research Commission

Grant: 1001

Arizona Biomedical Research Commission

Grant: 0011

Arizona Biomedical Research Commission

Grant: 05-901

Arizona Biomedical Research Commission

Grant: 4001

NIA NIH HHS

Grant: P30 AG019610

NIA NIH HHS

Grant: R01 AG029479

NIA NIH HHS

Grant: RF1 AG029479

NIA NIH HHS

Grant: R21 AG079189

NIA NIH HHS

Grant: R01 AG077700

National Institutes of Health

Grant: 5R01AG077700-02

Novel Tau-Targeted Radiohalogenated Agents for Alzheimer's Disease

National Institutes of Health

Grant: 2RF1AG029479-10

PET Imaging agents for a4b2 Nicotinic Receptors

National Institutes of Health

Grant: 5U24NS072026-03

National Brain and Tissue Resource for Parkinson's Disease and Related Disorders

National Institutes of Health

Grant: 2P30AG019610-11

Education and Information Transfer Core

Michael J. Fox Foundation for Parkinson's Research

National Institutes of Health

University of California, Irvine

FWCI

2.34

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.brainres.2025.149600

publisherhttps://doi.org/10.1016/j.brainres.2025.149600

publisherhttps://api.elsevier.com/content/article/PII:S0006899325001593?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0006899325001593?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40154862

Fields of Study

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology ResearchCholinesterase and Neurodegenerative Diseases03 medical and health sciences0302 clinical medicine

MeSH Terms

AgedAged, 80 and overAlzheimer DiseaseAutoradiographyFemaleFluorine RadioisotopesHippocampusHumansMaleMiddle AgedPyridinesPyrrolesReceptors, NicotinicAmyloid beta-Peptidestau ProteinsRadiopharmaceuticalsPositron-Emission TomographyPlaque, Amyloid

Keywords

SubiculumHippocampusNeuroscienceNicotinic agonistReceptorAlzheimer's diseaseHuman brainDiseasePathologyPsychologyMedicineInternal medicineDentate gyrusnicotinic receptorsAlzheimer’s diseaseHuman Tau[(18)F]flotazaHuman Aβ Plaques[(18)]Nifene[(125)I]ippiMaleAgingFluorine RadioisotopesPyridinesBiological Psychologytau ProteinsPlaque, AmyloidNeurodegenerativeReceptors, NicotinicArticleAlzheimer DiseaseAcquired Cognitive ImpairmentHumansPyrrolesAgedAged, 80 and overNeurology & NeurosurgeryAmyloid beta-PeptidesNeurosciencesAlzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)Middle AgedBrain DisordersPositron-Emission TomographyNeurologicalBiomedical ImagingAutoradiographyDementiaCognitive SciencesFemaleRadiopharmaceuticals

Sustainable Development Goals

SDG 0: Good health and well-being