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Silencing of miR490–3p by H. pylori activates DARPP-32 and induces resistance to gefitinib

Cancer Letters(2020)10.1016/j.canlet.2020.07.014Source: DataRank Database

Silencing of miR490–3p by H. pylori activates DARPP-32 and induces resistance to gefitinib is a research paper published in Cancer Letters (2020). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Open Access12 citations

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Enrichment:Funding (15 grants)Impact (FWCI 0.98)OA: greenTopics (64)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Shayan Khalafi ORCID,Zheng Chen ORCID,Julio Poveda ORCID,Dunfa Peng ORCID,Heng Lu ORCID

Live enrichment

PubMed:32735911 PMC:PMC7541786 OpenAlex:https://openalex.org/W3046155616

Research Career Scientist award

Grant: 1IK6BX003787

Research Career Scientist award

Grant: I01BX001179

U.S. National Institutes of Health

Grant: R01CA93999

Sylvester Comprehensive Cancer Center

Grant: P30CA240139

BLRD VA

Grant: IK6 BX003787

BLRD VA

Grant: I01 BX002115

NCI NIH HHS

Grant: R01 CA093999

NCI NIH HHS

Grant: R01 CA138833

BLRD VA

Grant: IK6 BX006300

NCI NIH HHS

Grant: R01 CA206564

National Institutes of Health

Grant: 2R01CA093999-07A2

Gene Amplification and Overexpression at 17q in Gastric Cancer: Darpp-32

National Institutes of Health

Grant: 3P30CA240139-02S3

The Sylvester Cancer Center Support Grant

National Institutes of Health

Grant: 2I01BX001179-09A1

Molecular Pathobiology of Gastric Carcinogenesis

National Institutes of Health

Grant: 5IK6BX003787-07

BLRD Research Career Scientist Award Application

U.S. Department of Veterans Affairs

FWCI

0.98

Citation Percentile

0.8%

Citation Trend

2021

2023

2024

2025

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7541786

publisherhttps://api.elsevier.com/content/article/PII:S0304383520303694?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0304383520303694?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.canlet.2020.07.014

Fields of Study

Helicobacter pylori-related gastroenterology studiesSignaling Pathways in DiseaseMicroRNA in disease regulation0301 basic medicine03 medical and health sciences0302 clinical medicineAnimalsCell Line, TumorDNA MethylationDopamine and cAMP-Regulated Phosphoprotein 32Drug Resistance, NeoplasmGefitinibHelicobacter InfectionsHelicobacter pyloriHumansMiceMice, Inbred C57BLMicroRNAsReceptor, Muscarinic M2Stomach Neoplasms

MeSH Terms

GefitinibAnimalsHumansMice, Inbred C57BLStomach NeoplasmsHelicobacter pyloriHelicobacter InfectionsDrug Resistance, NeoplasmDNA MethylationMicroRNAsReceptor, Muscarinic M2Cell Line, TumorMiceDopamine and cAMP-Regulated Phosphoprotein 32

Keywords

Gene silencingGefitinibCancer researchChemistryResistance (ecology)Cell biologyBiologyGeneticsCancerGeneEpidermal growth factor receptorMethylationGastric cancerStat3miRNADARPP-32AKTDopamine and cAMP-Regulated Phosphoprotein 32Receptor, Muscarinic M2Helicobacter pyloriDNA MethylationHelicobacter InfectionsMice, Inbred C57BLMiceMicroRNAsDrug Resistance, NeoplasmStomach NeoplasmsCell Line, TumorAnimalsHumans

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Silencing of miR490–3p by H. pylori activates DARPP-32 and induces resistance to gefitinib

FAIR Checklist

Authors (11)

Funding (15 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)