Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Proton pump inhibitors suppress DNA damage repair and sensitize treatment resistance in breast cancer by targeting fatty acid synthase

Cancer Letters(2021)10.1016/j.canlet.2021.03.026Source: DataRank Database

Proton pump inhibitors suppress DNA damage repair and sensitize treatment resistance in breast cancer by targeting fatty acid synthase is a research paper published in Cancer Letters (2021). On theSindex it has a DataRank of 0. It has been cited 57 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access57 citations

Download PDF

Cite:

Linked data & code

nct doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 3.38)OA: greenTopics (65)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (9)

Deren Li ORCID,Jacob A. Danielson ORCID,Evan H. Zhang ORCID,Zizheng Dong,Kathy D. Miller ORCID

Live enrichment

PubMed:33813001 PMC:PMC8167934 OpenAlex:https://openalex.org/W3149460283

US Department of Defense

Grant: W81XWH -16-1-0030

National Institutes of Health

Grant: R01 GM127656

Breast Cancer Research Foundation

FWCI

3.38

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://scholarworks.indianapolis.iu.edu/bitstreams/41eb83be-d127-47d7-98f6-5c2cf3f8faa4/download

publisherhttps://api.elsevier.com/content/article/PII:S030438352100149X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S030438352100149X?httpAccept=text/plain

repositoryhttps://hdl.handle.net/1805/34686

Fields of Study

Cancer, Lipids, and MetabolismDrug Transport and Resistance MechanismsMetabolomics and Mass Spectrometry StudiesAntineoplastic Combined Chemotherapy ProtocolsApoptosisBreast NeoplasmsChemoradiotherapyDNA DamageDNA End-Joining RepairData MiningDoxorubicinDrug Resistance, NeoplasmDrug SynergismElectronic Health RecordsEnzyme InhibitorsFatty Acid Synthase, Type IFemaleHumansLansoprazoleMCF-7 CellsPoly (ADP-Ribose) Polymerase-1Proton Pump InhibitorsRadiation Tolerance

MeSH Terms

Poly (ADP-Ribose) Polymerase-1Antineoplastic Combined Chemotherapy ProtocolsBreast NeoplasmsDNA DamageDoxorubicinDrug SynergismEnzyme InhibitorsFemaleHumansRadiation ToleranceApoptosisDrug Resistance, NeoplasmProton Pump InhibitorsFatty Acid Synthase, Type IData MiningElectronic Health RecordsChemoradiotherapyDNA End-Joining RepairMCF-7 CellsLansoprazole

Keywords

Fatty acid synthasePARP1DNA repairDNA damageCancerCancer researchCancer cellApoptosisBreast cancerPharmacologyMedicineBiologyInternal medicineEnzymeLipid metabolismBiochemistryPoly ADP ribose polymeraseDNAPolymeraseDNA damage repairenantiomerProton Pump Inhibitor

Sustainable Development Goals

SDG 0: Good health and well-being