Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

DNMT and EZH2 inhibitors synergize to activate therapeutic targets in hepatocellular carcinoma

Cancer Letters(2022)10.1016/j.canlet.2022.215899Source: DataRank Database

DNMT and EZH2 inhibitors synergize to activate therapeutic targets in hepatocellular carcinoma is a research paper published in Cancer Letters (2022). On theSindex it has a DataRank of 0. It has been cited 74 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access74 citations

Download PDF

Cite:

Linked data & code

geo

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)OA: greenTopics (38)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (13)

Hongtao Li ORCID,Rachel Shereda,Qianjin Lu ORCID,Daniel J. Weisenberger ORCID,Casey L. O’Connell ORCID

Live enrichment

PubMed:36087682 PMC:PMC9563073

National Cancer Institute

Grant: / NCI R50CA243878

National Cancer Institute

Grant: P30 CA014089

National Cancer Institute

Grant: R35 CA209859

NCI NIH HHS

Grant: R50 CA243878

National Institutes of Health

Grant: 5R35CA209859-05

Targeting DNA Methylation and the Cancer Epigenome

National Institutes of Health

Grant: 1R50CA243878-01

Research Specialist Support-Targeting DNA Methylation and the Cancer Epigenome

National Institutes of Health

Grant: 3P30CA014089-17S1

USC COMPREHENSIVE CANCER CENTER (CORE) SUPPORT

National Institutes of Health

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9563073

publisherhttps://api.elsevier.com/content/article/PII:S0304383522003834?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0304383522003834?httpAccept=text/plain

https://doi.org/10.1016/j.canlet.2022.215899

https://pubmed.ncbi.nlm.nih.gov/36087682

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Cell Line, TumorNucleosomesHumansCarcinoma, HepatocellularLiver NeoplasmsHistonesDNAEnzyme InhibitorsGene Expression Regulation, NeoplasticPolycomb Repressive Complex 2Enhancer of Zeste Homolog 2 ProteinDNA (Cytosine-5-)-MethyltransferasesDecitabine

Keywords

DNA methylationHCCGene Expression5-Aza-CdREpigenetic TherapyEzh2Chromatin AccessibilityPrc2Gsk-126Carcinoma, HepatocellularLiver NeoplasmsPolycomb Repressive Complex 2DNADecitabineNucleosomesGene Expression Regulation, NeoplasticHistonesCell Line, TumorHumansEnhancer of Zeste Homolog 2 ProteinDNA (Cytosine-5-)-MethyltransferasesEnzyme Inhibitors

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of Cellular senescence-related genes: predicting prognosis in hepatocellular carcinoma

10.6084/m9.figshare.24355052.v1figshare

Additional file 1 of Cellular senescence-related genes: predicting prognosis in hepatocellular carcinoma

10.6084/m9.figshare.24355052figshare

Additional file 2 of Cellular senescence-related genes: predicting prognosis in hepatocellular carcinoma

10.6084/m9.figshare.24355141.v1figshare

Additional file 2 of Cellular senescence-related genes: predicting prognosis in hepatocellular carcinoma

10.6084/m9.figshare.24355141figshare

Additional file 2 of Phosphorylation of EZH2 differs HER2-positive breast cancer invasiveness in a site-specific manner

10.6084/m9.figshare.24264774figshare

Additional file 2 of Phosphorylation of EZH2 differs HER2-positive breast cancer invasiveness in a site-specific manner

10.6084/m9.figshare.24264774.v1figshare

Additional file 1 of Phosphorylation of EZH2 differs HER2-positive breast cancer invasiveness in a site-specific manner

10.6084/m9.figshare.24264659figshare

Additional file 1 of Phosphorylation of EZH2 differs HER2-positive breast cancer invasiveness in a site-specific manner

10.6084/m9.figshare.24264659.v1figshare

DNMT and EZH2 inhibitors synergize to activate therapeutic targets in hepatocellular carcinoma

FAIR Checklist

Authors (13)

Funding (8 grants)

Open Access

Topics

Linked Datasets (8)

Annotations (Europe PMC)