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Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model

Cancer Letters(2025)10.1016/j.canlet.2025.217444Source: DataRank Database

Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model is a research paper published in Cancer Letters (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)OA: hybridTopics (34)IDs (PubMed)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Mohamed A. Gouda ORCID,Shriya Pandey,Neeraj Chauhan ORCID,Tao Shen ORCID,Xueqing Hu ORCID

Live enrichment

PubMed:39778760

NIGMS NIH HHS

Grant: P20 GM103639

NCI NIH HHS

Grant: P30 CA016672

NCI NIH HHS

Grant: R01 CA242845

NCI NIH HHS

Grant: R01 CA260729

NIGMS NIH HHS

Grant: P30 GM154635

NCI NIH HHS

Grant: R01 CA273168

NCI NIH HHS

Grant: P30 CA225520

NCI NIH HHS

Grant: R01 CA247234

NCI NIH HHS

Grant: R01 CA264932

hybridLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.canlet.2025.217444

publisherhttps://api.elsevier.com/content/article/PII:S0304383525000084?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0304383525000084?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12228837/pdf/nihms-2047556.pdf

Fields of Study

AnimalsCachexiaHumansCell Line, TumorProto-Oncogene Proteins c-retProtein Kinase InhibitorsMuscle, SkeletalMicePyrazolesXenograft Model Antitumor AssaysMaleSignal TransductionCell ProliferationPyridines

MeSH Terms

Keywords

AnorexiaCancer cachexiaKinase inhibitorMuscle atrophyRETSelpercatinib