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MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

Cancer Cell(2020)10.1016/j.ccell.2020.11.004Source: DataRank Database

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway is a research paper published in Cancer Cell (2020). On theSindex it has a DataRank of 0. It has been cited 237 times.

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Open Access237 citations

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cellosaurus uniprot doi

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Enrichment:Funding (5 grants)OA: bronzeTopics (29)IDs (PubMed, PMC)Annotations (3)

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Authors (17)

Changzheng Lu ORCID,Qihuang Jin ORCID,Huiming Lu ORCID,Xiang Chen ORCID,Lei Tian ORCID

Live enrichment

PubMed:33338427 PMC:PMC8666006

NIGMS NIH HHS

Grant: R01 GM047251

NCI NIH HHS

Grant: P01 CA092584

NCI NIH HHS

Grant: R01 CA162804

National Institutes of Health

Cancer Prevention and Research Institute of Texas

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

publisherhttp://www.cell.com/article/S1535610820305961/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1535610820305961?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1535610820305961?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8666006

MeSH Terms

Cell Line, TumorHela CellsAnimalsHumansMiceNeoplasmsChromosome AberrationsDNA Repair EnzymesExodeoxyribonucleasesNucleotidyltransferasesMembrane ProteinsDNA, Single-StrandedSignal TransductionDNA RepairReplication Protein ADNA Mismatch RepairDNA Breaks, Single-StrandedMutL Protein Homolog 1STING ProteinCyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase

Keywords

Mismatch repairMLH1Chromosome InstabilityRad51Dna BreaksCytosolic DnaExonuclease 1Cgas-stingRpa Exhaustion

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

FAIR Checklist

Authors (17)

Funding (5 grants)

Open Access

Topics

Annotations (Europe PMC)