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DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

Cancer Cell(2020)10.1016/j.ccell.2020.11.006Source: DataRank Database

DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity is a research paper published in Cancer Cell (2020). On theSindex it has a DataRank of 0. It has been cited 280 times.

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Open Access280 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)OA: bronzeTopics (69)IDs (PubMed)SDGs (1)

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Authors (26)

Junhong Guan ORCID,Steve Lu ORCID,Qihuang Jin ORCID,Benoı̂t Rousseau ORCID,Tianshi Lu ORCID

Live enrichment

PubMed:33338425

University of Texas Southwestern Medical Center

Grant: RP180725

Cancer Prevention and Research Institute of Texas

Grant: RR150072

Cancer Prevention and Research Institute of Texas

Grant: RR160101

National Institutes of Health

Grant: 1R01CA245318-01A1

Antigen-independent prediction and biomarker identification of cancer-specific T cells

National Institutes of Health

Grant: 5P30CA142543

NCI NIH HHS

Grant: P30 CA008748

NCI NIH HHS

Grant: R01 CA245318

NCI NIH HHS

Grant: P30 CA142543

bronzeLicense: Elsevier Non-Commercial

publisherhttp://www.cell.com/article/S1535610820305985/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1535610820305985?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1535610820305985?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9477183

https://doi.org/10.1016/j.ccell.2020.11.006

Fields of Study

03 medical and health sciences0302 clinical medicineAnimalsCell Line, TumorDNA Mismatch RepairDown-RegulationFemaleGene Expression Regulation, NeoplasticHumansImmune Checkpoint InhibitorsInterferon-betaMembrane ProteinsMiceMutL Protein Homolog 1Neoplasm TransplantationNeoplasmsNucleotidyltransferasesPrognosisSignal TransductionSTING ProteinCyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase

MeSH Terms

AnimalsCell Line, TumorDNA Mismatch RepairDown-RegulationFemaleGene Expression Regulation, NeoplasticHumansImmune Checkpoint InhibitorsInterferon-betaMembrane ProteinsMiceMutL Protein Homolog 1Neoplasm TransplantationNeoplasmsNucleotidyltransferasesPrognosisSignal TransductionSTING ProteinCyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase

Keywords

Down-RegulationMembrane ProteinsInterferon-betaCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthasePrognosisDNA Mismatch RepairNucleotidyltransferasesGene Expression Regulation, NeoplasticMiceSTING ProteinCell Line, TumorNeoplasmsAnimalsHumansFemaleMutL Protein Homolog 1Immune Checkpoint InhibitorsNeoplasm TransplantationSignal TransductionDNA sensingMLH1MSISTINGT cell infiltrationcGAScancercheckpoint blockadecytosolic DNAmismatch repair

Sustainable Development Goals

SDG 3: 3. Good health