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Merlin/NF2 Loss-Driven Tumorigenesis Linked to CRL4DCAF1-Mediated Inhibition of the Hippo Pathway Kinases Lats1 and 2 in the Nucleus

Cancer Cell(2014)10.1016/j.ccr.2014.05.001Source: DataRank Database

Merlin/NF2 Loss-Driven Tumorigenesis Linked to CRL4DCAF1-Mediated Inhibition of the Hippo Pathway Kinases Lats1 and 2 in the Nucleus is a research paper published in Cancer Cell (2014). On theSindex it has a DataRank of 0.838. It has been cited 265 times.

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0.838DataRank · unranked

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265 citations

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Enrichment:Funding (2 grants)OA: bronzeTopics (26)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed)SDGs (1)

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0.838

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Authors (12)

Jonathan Cooper,Lu Zhou ORCID,Chenyi Yang,Hediye Erdjument-Bromage,David Zagzag ORCID

Live enrichment

PubMed:21097893

National Institutes of Health

Grant: 2P30CA008748-43

MOUSE GENETICS

National Institutes of Health

Grant: 5R01CA152975-02

Mechanism of Merlin-mediated contact inhibition and tumor suppression.

bronzeLicense: Elsevier Non-Commercial

publisherhttp://www.cell.com/article/S1535610814001895/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1535610814001895?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1535610814001895?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/4126592

https://doi.org/10.1016/j.ccr.2014.05.001

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

AdultMaleCancer ResearchAdolescentMice, NudeMiceAnimalsHumansHippo Signaling PathwayChildAdaptor Proteins, Signal TransducingAgedAged, 80 and overCell NucleusEpistasis, GeneticCell BiologyHep G2 CellsGene Expression Regulation, NeoplasticMice, Inbred C57BLCell Transformation, NeoplasticOncologyFemaleCarrier Proteins

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 1 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 2 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 2 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 3 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 3 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 4 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 4 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 5 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 5 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 6 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 6 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 7 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 7 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 8 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 8 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 9 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 9 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 10 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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Additional file 10 of Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency

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