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Mutation in RyR2-FKBP Binding site alters Ca2+ signaling modestly but increases “arrhythmogenesis” in human stem cells derived cardiomyocytes

Cell Calcium(2021)10.1016/j.ceca.2021.102500Source: DataRank Database

Mutation in RyR2-FKBP Binding site alters Ca2+ signaling modestly but increases “arrhythmogenesis” in human stem cells derived cardiomyocytes is a research paper published in Cell Calcium (2021). On theSindex it has a DataRank of 0. It has been cited 14 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access14 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 1.32)OA: greenTopics (39)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Yanli Xia ORCID,Taylor J. Renzo,Xiao‐Hua Zhang ORCID,Martin Morad ORCID,José‐Carlos Fernández‐Morales

Live enrichment

PubMed:34813985 PMC:PMC8752506 OpenAlex:https://openalex.org/W3212917415

National Institutes of Health

Grant: Ro1HL153504

National Institutes of Health

Grant: R56HL147054

NHLBI NIH HHS

Grant: R01 HL153504

FWCI

1.32

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

greenLicense: https://doi.org/10.15223/policy-004

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8752506

publisherhttps://api.elsevier.com/content/article/PII:S0143416021001548?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0143416021001548?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ceca.2021.102500

Fields of Study

Cardiac electrophysiology and arrhythmiasIon channel regulation and functionNeuroscience and Neural EngineeringBinding SitesCalciumCalcium SignalingHumansInduced Pluripotent Stem CellsMutationMyocytes, CardiacRyanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumTacrolimus Binding Proteins

MeSH Terms

Binding SitesCalciumHumansMutationSarcoplasmic ReticulumRyanodine Receptor Calcium Release ChannelCalcium SignalingTacrolimus Binding ProteinsMyocytes, CardiacInduced Pluripotent Stem Cells

Keywords

FKBPRyanodine receptor 2Cell biologyMutationBiologyChemistryGeneticsRyanodine receptorGeneEndoplasmic reticulumHuman Induced Pluripotent Stem CellsSkeletal MyopathyCrispr/cas9Cicr GainRyanodine Receptor MutationFkbp Binding Site

Sustainable Development Goals

SDG 0: Good health and well-being