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Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex

Cell(2020)10.1016/j.cell.2020.01.007Source: DataRank Database

Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex is a research paper published in Cell (2020). On theSindex it has a DataRank of 0. It has been cited 253 times.

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Open Access253 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)OA: bronzeTopics (29)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (17)

Youwen Zhuang ORCID,Ting-Hai Xu ORCID,Zhiwei Feng ORCID,X. Edward Zhou ORCID,Maozi Chen ORCID

Live enrichment

PubMed:32004460 PMC:PMC8247115

NIDA NIH HHS

Grant: P30 DA035778

NIDA NIH HHS

Grant: R01 DA025612

NIGMS NIH HHS

Grant: R01 GM127710

NIGMS NIH HHS

Grant: R35 GM128641

National Institute on Drug Abuse

Ministry of Science and Technology of the People's Republic of China

National Institutes of Health

Influential Citations

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

BRONZEhttp://www.cell.com/article/S0092867420300544/pdf

publisherhttp://www.cell.com/article/S0092867420300544/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0092867420300544?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867420300544?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8247115

Fields of Study

MedicineBiologyChemistry

MeSH Terms

CHO CellsAnimalsHumansCricetulusSpodopteraGTP-Binding Protein alpha Subunits, Gi-GoReceptor, Cannabinoid, CB2Cryoelectron MicroscopySignal TransductionBinding SitesProtein BindingCricetinaeCannabinoid Receptor AgonistsCannabinoid Receptor AntagonistsMolecular Docking SimulationSf9 Cells

Keywords

Cb2 AgonistCryo-em StructureCb2 Inverse Agonist3D Structure Of Cannabinoid Receptor Cb2Activation Mechanisms Of Cb2 And Cb1Agonist-bound Cb2- Gi Signaling ComplexCb2 Coupling Specificity For GiCb2 Drug DiscoveryGi Coupling VersatilityResidual Energy Contribution

Additional file 1 of Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis

10.6084/m9.figshare.22599856.v1figshare

Additional file 1 of Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis

10.6084/m9.figshare.22599856figshare