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Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma

Cell(2020)10.1016/j.cell.2020.04.047Source: DataRank Database

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma is a research paper published in Cell (2020). On theSindex it has a DataRank of 0. It has been cited 141 times.

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Enrichment:Funding (69 grants)OA: hybridTopics (58)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC)Annotations (3)SDGs (1)

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Authors (66)

Sachin Kumar ORCID,Leo J.Y. Kim ORCID,Florence M.G. Cavalli ORCID,David Przelicki,John Wojcik ORCID

Live enrichment

PubMed:32445698 PMC:PMC10782558

Ontario Genomics Institute

Grant: OGI-055

Cancer Prevention and Research Institute of Texas

Grant: RR170023

National Institutes of Health

Grant: CA203101

National Institutes of Health

Grant: CA148699

National Institutes of Health

Grant: CA197718

National Institutes of Health

Grant: CA159859

National Institutes of Health

Grant: NS089272

National Institutes of Health

Grant: NS103434

National Institutes of Health

Grant: NS087913

National Institutes of Health

Grant: CA238662

National Institutes of Health

Grant: CA171652

National Institutes of Health

Grant: CA169117

National Institutes of Health

Grant: CA154130

Baylor College of Medicine

Grant: 1097737

Stand Up To Cancer Canada

Grant: SU2C-AACR-DT-19-15

Stand Up To Cancer

Grant: SU2C-AACR-DT1113

NCI NIH HHS

Grant: R01 CA159859

NCI NIH HHS

Grant: R01 CA171652

NINDS NIH HHS

Grant: R01 NS087913

The Brain Tumour Charity

Grant: GN-000379

NCI NIH HHS

Grant: R01 CA154130

NCI NIH HHS

Grant: R35 CA197718

NCI NIH HHS

Grant: R01 CA148699

NCI NIH HHS

Grant: R01 CA169117

NCI NIH HHS

Grant: F30 CA203101

NINDS NIH HHS

Grant: R01 NS089272

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 7F30CA203101-03

Targeting TCA cycle in Brain Tumor Initiating Cells

National Institutes of Health

Grant: 5R01CA154130-02

Targeting Brain Tumor Stem Cells Through Novel Therapeutic Combinations

National Institutes of Health

Grant: 1R01CA171652-01A1

Instructive Cues in Glioblastoma Hierarchies

National Institutes of Health

Grant: 5R01NS087913-04

Metabolism Informs Intertumoral & Intratumoral Heterogeneity

National Institutes of Health

Grant: 7R35CA197718-03

Dynamic Complexity of Brain Tumor Stem Cells

European Commission

Grant: 115766

Unrestricted Leveraging of Targets for Research Advancement and Drug Discovery

National Institutes of Health

Grant: 5R01CA169117-03

Targeting Ferritin in Glioblastoma

Bear Necessities Pediatric Cancer Foundation

Brain Tumour Charity

Ontario Research Foundation

Terry Fox Research Institute

V Foundation for Cancer Research

Children's Cancer Research Fund

Genome British Columbia

Genome Canada

Hospital for Sick Children

Meso Scale Diagnostics

Pediatric Brain Tumor Foundation

Alex's Lemonade Stand Foundation for Childhood Cancer

Canadian Institutes of Health Research

Cancer Research UK

Pfizer

Takeda Pharmaceuticals U.S.A.

Wellcome Trust

Canadian Cancer Society

Eshelman Institute for Innovation, University of North Carolina at Chapel Hill

Government of Canada

Government of Ontario

Janssen Pharmaceuticals

Mitacs

Innovative Medicines Initiative

Novartis

Swifty Foundation

Boehringer Ingelheim

Children's Brain Tumor Foundation

Worldwide Cancer Research

American Association for Cancer Research

Ontario Institute for Cancer Research

Entertainment Industry Foundation

Merck KGaA

University of Toronto

Wellcome Trust

hybridLicense: Elsevier Non-Commercial

publisherhttps://api.elsevier.com/content/article/PII:S0092867420305535?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867420305535?httpAccept=text/plain

https://doi.org/10.1016/j.cell.2020.04.047

http://www.cell.com/article/S0092867420305535/pdf

https://pubmed.ncbi.nlm.nih.gov/32445698

Fields of Study

0301 basic medicine03 medical and health sciencesAnimalsBrain NeoplasmsCell LineCell ProliferationDNA MethylationEpendymomaEpigenomeEpigenomicsHistonesHumansInfantInfratentorial NeoplasmsLysineMaleMice, Inbred C57BLMutation

MeSH Terms

Cell LineAnimalsMice, Inbred C57BLHumansEpendymomaBrain NeoplasmsInfratentorial NeoplasmsLysineHistonesCell ProliferationDNA MethylationMutationInfantMaleEpigenomicsEpigenome

Keywords

MicroenvironmentEpendymomaEpigeneticsCancer MetabolismPaediatric CancerHindbrain DevelopmentEpigenomicsMaleInfratentorial NeoplasmsInbred C57BLCell LineHistonesMiceEpigenomeAnimalsHumansCell ProliferationBrain NeoplasmsLysineInfantcancer metabolism; ependymoma; epigenetics; hindbrain development; microenvironment; paediatric cancer; Animals; Brain Neoplasms; Cell Line; Cell Proliferation; DNA Methylation; Ependymoma; Epigenome; Epigenomics; Histones; Humans; Infant; Infratentorial Neoplasms; Lysine; Male; Mice, Inbred C57BL; MutationDNA MethylationMice, Inbred C57BLMutation

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma

10.6084/m9.figshare.13161431.v1figshare

Additional file 1 of Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma

10.6084/m9.figshare.13161431figshare

Additional file 1 of Characterizing DNA methylation signatures and their potential functional roles in Merkel cell carcinoma

10.6084/m9.figshare.15179185.v1figshare

Additional file 1 of Characterizing DNA methylation signatures and their potential functional roles in Merkel cell carcinoma

10.6084/m9.figshare.15179185figshare

Additional file 2 of Characterizing DNA methylation signatures and their potential functional roles in Merkel cell carcinoma

10.6084/m9.figshare.15179188.v1figshare