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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

Cell(2020)10.1016/j.cell.2020.09.033Source: DataRank Database

SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2 is a research paper published in Cell (2020). On theSindex it has a DataRank of 11.0. It has been cited 1,206 times, with 200 citing works in its 1-hop citation network.

N/A

11.0DataRank · unranked

Scored on demand from live citation data

Open Access1,206 citations · 200 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (23 grants)Impact (FWCI 21.13)OA: bronzeTopics (106)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 10%Citation Network 90%

Base Score Contribution

1.1

From this paper's citation signal

Citation Network Contribution

9.9

From 200 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 200 citers.

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Blood202146 citations19 referencesContributes 0.203
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Bristol Research (University of Bristol)2021589 citations34 referencesContributes 0.188

Authors (36)

Daniel R. Sandoval ORCID,Charlotte B. Spliid ORCID,Jessica Pihl ORCID,Hailee R. Perrett ORCID,Chelsea D. Painter ORCID

Live enrichment

PubMed:32970989 PMC:PMC7489987 OpenAlex:https://openalex.org/W3085153423

U.S. Department of Defense

Grant: W81XWH-20-1-0270

U.S. Department of Defense

Grant: Fluomics/NOSI U19 AI135972

Danmarks Grundforskningsfond

Grant: AI007245

Danmarks Grundforskningsfond

Grant: GM007753

Alfred Benzon Foundation

Grant: R01 AI146779

National Heart, Lung, and Blood Institute

Grant: P01 HL131474

National Science Foundation

Grant: 2031989

RAPID: Glycan coreceptors for SARS-CoV-2 spike protein

Bill and Melinda Gates Foundation

Grant: OPP1170236

Bill and Melinda Gates Foundation

Grant: DNRF107

NHLBI NIH HHS

Grant: P01 HL107150

NIGMS NIH HHS

Grant: R01 GM128464

NIDDK NIH HHS

Grant: T32 DK007044

NHLBI NIH HHS

Grant: K12 HL141956

NIGMS NIH HHS

Grant: T32 GM008313

NIAID NIH HHS

Grant: U19 AI135972

NIAID NIH HHS

Grant: T32 AI007245

NICHD NIH HHS

Grant: DP2 HD087954

NIGMS NIH HHS

Grant: T32 GM007753

National Institutes of Health

Grant: 5P01HL131474-03

Protein Glycosylation in the Coagulopathy and Inflammation of Sepsis

National Institutes of Health

Grant: 3R01AI146779-01S1

Epitope focusing to the receptor binding motif for a universal coronavirus vaccine

National Institutes of Health

Grant: 5U19AI135972-04

Fluomics: The Next Generation

National Science Foundation

National Heart, Lung, and Blood Institute

FWCI

21.13

Citation Percentile

1.0%

Citation Trend

2019

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S0092867420312307/pdf

publisherhttp://www.cell.com/article/S0092867420312307/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0092867420312307?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867420312307?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cell.2020.09.033

Fields of Study

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesInfluenza Virus Research Studies0301 basic medicine0303 health sciences03 medical and health sciencesAmino Acid SequenceAngiotensin-Converting Enzyme 2BetacoronavirusBinding SitesCOVID-19Cell LineCoronavirus InfectionsHeparinHeparan SulfateHumansKidneyLungMolecular Dynamics SimulationPandemicsPeptidyl-Dipeptidase APneumonia, ViralProtein BindingProtein DomainsRecombinant ProteinsSARS-CoV-2Spike Glycoprotein, CoronavirusVirus Internalization

MeSH Terms

Protein DomainsBetacoronavirusAngiotensin-Converting Enzyme 2COVID-19SARS-CoV-2Amino Acid SequenceBinding SitesCell LineHeparinHeparan SulfateHeparitin SulfateHumansKidneyPeptidyl-Dipeptidase ALungPneumonia, ViralProtein BindingRecombinant ProteinsCoronavirus InfectionsVirus InternalizationMolecular Dynamics SimulationPandemicsSpike Glycoprotein, Coronavirus

Keywords

BiologyHeparan sulfateSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakCell biologyBiochemistryCellDiseaseInternal medicineInfectious disease (medical specialty)HeparinCoronavirusLung Epithelial CellsPseudotyped VirusSpike ProteinsCovid-19Sars-cov-2Heparan Sulfate-binding ProteinsBiomedical and clinical sciencesCoronavirusesKidneyMedical and Health SciencesCoronaviruses Therapeutics and InterventionsViralLungBiological SciencesSpike GlycoproteinRecombinant ProteinsInfectious DiseasesAngiotensin-Converting Enzyme 2InfectionCoronavirus InfectionsProtein BindingPneumonia, Viral610Molecular Dynamics SimulationPeptidyl-Dipeptidase AGeneral Biochemistry, Genetics and Molecular BiologyArticleCell LineBetacoronavirusProtein DomainsHumansAmino Acid SequencePandemicsBinding Sites500PneumoniaVirus InternalizationEmerging Infectious DiseasesBiochemistry and Cell BiologyHeparitin SulfateDevelopmental Biology

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of Methylprednisolone, venous thromboembolism, and association with heparin to 30 days in hospital survival in severe Covid-19 pneumonia

10.6084/m9.figshare.17913099.v1figshare

Additional file 1 of Methylprednisolone, venous thromboembolism, and association with heparin to 30 days in hospital survival in severe Covid-19 pneumonia

10.6084/m9.figshare.17913099figshare

Additional file 1 of Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal

10.6084/m9.figshare.20962344.v1figshare

Additional file 1 of Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal

10.6084/m9.figshare.20962344figshare

Additional file 1 of Recombinant human plasma gelsolin reverses increased permeability of the blood–brain barrier induced by the spike protein of the SARS-CoV-2 virus

10.6084/m9.figshare.21628627.v1figshare

Additional file 1 of Recombinant human plasma gelsolin reverses increased permeability of the blood–brain barrier induced by the spike protein of the SARS-CoV-2 virus

10.6084/m9.figshare.21628627figshare

Additional file 1 of ApoE4 associated with severe COVID-19 outcomes via downregulation of ACE2 and imbalanced RAS pathway

10.6084/m9.figshare.26567585.v1figshare

Additional file 1 of ApoE4 associated with severe COVID-19 outcomes via downregulation of ACE2 and imbalanced RAS pathway

10.6084/m9.figshare.26567585figshare

Additional file 3 of Development of nanoparticles incorporated with quercetin and ACE2-membrane as a novel therapy for COVID-19

10.6084/m9.figshare.26705682.v1figshare

Additional file 3 of Development of nanoparticles incorporated with quercetin and ACE2-membrane as a novel therapy for COVID-19

10.6084/m9.figshare.26705682figshare

Additional file 1 of The mutation of Japanese encephalitis virus envelope protein residue 389 attenuates viral neuroinvasiveness

10.6084/m9.figshare.26729884.v1figshare

Additional file 1 of The mutation of Japanese encephalitis virus envelope protein residue 389 attenuates viral neuroinvasiveness

10.6084/m9.figshare.26729884figshare

Additional file 3 of Tilorone mitigates the propagation of α-synucleinopathy in a midbrain-like organoid model

10.6084/m9.figshare.26945301.v1figshare

Additional file 3 of Tilorone mitigates the propagation of α-synucleinopathy in a midbrain-like organoid model

10.6084/m9.figshare.26945301figshare

Additional file 1 of Tilorone mitigates the propagation of α-synucleinopathy in a midbrain-like organoid model

10.6084/m9.figshare.26945295.v1figshare

Additional file 2 of Tilorone mitigates the propagation of α-synucleinopathy in a midbrain-like organoid model

10.6084/m9.figshare.26945298figshare

Additional file 1 of Tilorone mitigates the propagation of α-synucleinopathy in a midbrain-like organoid model

10.6084/m9.figshare.26945295figshare

Additional file 2 of Tilorone mitigates the propagation of α-synucleinopathy in a midbrain-like organoid model

10.6084/m9.figshare.26945298.v1figshare

Additional file 4 of Development of nanoparticles incorporated with quercetin and ACE2-membrane as a novel therapy for COVID-19

10.6084/m9.figshare.26705685figshare

Additional file 4 of Development of nanoparticles incorporated with quercetin and ACE2-membrane as a novel therapy for COVID-19

10.6084/m9.figshare.26705685.v1figshare

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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (36)

Funding (23 grants)

Impact

Open Access

Topics

Linked Datasets (25)

Annotations (Europe PMC)

Related Papers (10)