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Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

Cell(2020)10.1016/j.cell.2020.11.025Source: DataRank Database

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes is a research paper published in Cell (2020). On theSindex it has a DataRank of 1.1. It has been cited 1,650 times.

N/A

1.1DataRank · unranked

Scored on demand from live citation data

Open Access1,650 citations

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Linked data & code

geo cellosaurus arrayexpress doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (21 grants)Impact (FWCI 22.72)OA: bronzeTopics (60)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

1.1

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (16)

Bhesh Raj Sharma ORCID,Shraddha Tuladhar ORCID,Evan P. Williams ORCID,Lillian Zalduondo ORCID,Parimal Samir ORCID

Live enrichment

PubMed:33278357 PMC:PMC7674074 OpenAlex:https://openalex.org/W3105908160

National Institutes of Health

Grant: AR056296

National Institutes of Health

Grant: AI124346

National Institutes of Health

Grant: AI101935

National Institutes of Health

Grant: CA253095

National Institutes of Health

Grant: 63/106,012

National Institutes of Health

Grant: NR-52281

NIAID NIH HHS

Grant: R01 AI101935

NIAID NIH HHS

Grant: R37 AI101935

NIAID NIH HHS

Grant: R01 AI124346

NCI NIH HHS

Grant: R35 CA253095

NIAMS NIH HHS

Grant: R01 AR056296

National Institutes of Health

Grant: 5R01AR056296-15

Role of IL-1alpha signaling in inflammatory diseases and host defense

National Institutes of Health

Grant: 5R01AI124346-07

Innate immune signaling and stress response

National Institutes of Health

Grant: 5R37AI101935-10

Inflammatory Caspases in Innate Immunity and Inflammation

National Institutes of Health

Grant: 5R35CA253095-04

Innate immune sensors, inflammasomes, and inflammasome-mediated processes in cancer

RIKEN

National Institute of Allergy and Infectious Diseases

American Lebanese Syrian Associated Charities

Genentech

Centers for Disease Control and Prevention

Ministry of Education, Culture, Sports, Science and Technology

FWCI

22.72

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: CC BY ND

journalhttp://www.cell.com/article/S0092867420315427/pdf

publisherhttp://www.cell.com/article/S0092867420315427/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0092867420315427?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867420315427?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cell.2020.11.025

Fields of Study

COVID-19 Clinical Research StudiesInflammasome and immune disordersSARS-CoV-2 and COVID-19 Research0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

THP-1 CellsCytokine Release SyndromeCOVID-19AnimalsDisease Models, AnimalFemaleHumansInflammationInterferon-gammaMaleMice, TransgenicTumor Necrosis Factor-alphaCell DeathLymphohistiocytosis, HemophagocyticMiceAntibodies, NeutralizingHuman Umbilical Vein Endothelial Cells

Keywords

BiologyCytokineImmunologyTumor necrosis factor alphaShock (circulatory)InflammationInterferon gammaProgrammed cell deathVirologyApoptosisGeneticsInternal medicineTNF-αIFN-γNecroptosisPyroptosisCytokine StormPanoptosisCovid-19Sars-cov-2MaleCell DeathTHP-1 CellsTumor Necrosis Factor-alphaMice, TransgenicAntibodies, NeutralizingGeneral Biochemistry, Genetics and Molecular BiologyArticleLymphohistiocytosis, HemophagocyticDisease Models, AnimalInterferon-gammaMiceHuman Umbilical Vein Endothelial CellsAnimalsHumansFemaleCytokine Release Syndrome

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being