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Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages

Cell(2021)10.1016/j.cell.2021.04.038Source: DataRank Database

Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages is a research paper published in Cell (2021). On theSindex it has a DataRank of 9.0. It has been cited 379 times, with 200 citing works in its 1-hop citation network.

N/A

9.0DataRank · unranked

Scored on demand from live citation data

Open Access379 citations · 200 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 22.73)OA: bronzeTopics (71)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 10%Citation Network 90%

Base Score Contribution

0.891

From this paper's citation signal

Citation Network Contribution

8.1

From 200 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 200 citers.

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Clinical Cancer Research2022215 citations46 referencesContributes 0.117
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Cell Reports2021356 citations51 referencesContributes 0.115
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Journal of Hepatology202455 citations39 referencesContributes 0.103

Authors (17)

Nivedita Chowdhury ORCID,Scott M. Haake ORCID,Casey R. Ager ORCID,Vinson Wang,Lukas Vlahos ORCID

Live enrichment

PubMed:34019793 PMC:PMC8479759 OpenAlex:https://openalex.org/W3160973971

NCI NIH HHS

Grant: R01 CA127153

NCI NIH HHS

Grant: F30 CA260765

NCI NIH HHS

Grant: P30 CA006973

NCI NIH HHS

Grant: R35 CA197745

NCI NIH HHS

Grant: K12 CA090625

NCI NIH HHS

Grant: P50 CA058236

NCI NIH HHS

Grant: P30 CA013696

NCI NIH HHS

Grant: R01 CA217987

NIH HHS

Grant: S10 OD021764

NCI NIH HHS

Grant: R38 CA231577

NIH HHS

Grant: S10 OD012351

NCI NIH HHS

Grant: U01 CA217858

US Department of Defense

NIH

FWCI

22.73

Citation Percentile

1.0%

Influential Citations

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

journalhttp://www.cell.com/article/S0092867421005730/pdf

BRONZEhttp://www.cell.com/article/S0092867421005730/pdf

publisherhttp://www.cell.com/article/S0092867421005730/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0092867421005730?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867421005730?httpAccept=text/plain

Fields of Study

Single-cell and spatial transcriptomicsImmune cells in cancerCancer Immunotherapy and BiomarkersMedicineBiologyAdultApolipoproteins EBiomarkers, TumorCarcinoma, Renal CellCohort StudiesFemaleGene ExpressionGene Expression Regulation, NeoplasticHumansKidneyKidney NeoplasmsLymphocytes, Tumor-InfiltratingMacrophagesMaleMembrane GlycoproteinsMiddle AgedNeoplasm Recurrence, LocalPrognosisReceptors, ComplementReceptors, ImmunologicSequence Analysis, RNASingle-Cell AnalysisTumor MicroenvironmentTumor-Associated Macrophages

MeSH Terms

Tumor-Associated MacrophagesAdultApolipoproteins ECarcinoma, Renal CellFemaleHumansKidneyKidney NeoplasmsMacrophagesMaleMembrane GlycoproteinsMiddle AgedNeoplasm Recurrence, LocalPrognosisReceptors, ComplementReceptors, ImmunologicBiomarkers, TumorCohort StudiesGene ExpressionGene Expression Regulation, NeoplasticLymphocytes, Tumor-InfiltratingSequence Analysis, RNASingle-Cell AnalysisTumor Microenvironment

Keywords

BiologyCellCell biologyCancer researchImmunologyComputational biologyGeneticsImmunotherapyClusteringTregTumor MicroenvironmentGene Regulatory NetworksClear Cell Renal CarcinomaPost-surgical RecurrenceCd8 T cellSingle-cell Rna SequencingProtein Activity InferenceTumor-infiltrating Macrophage

Sustainable Development Goals

SDG 0: Good health and well-being