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Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases

Cell(2022)10.1016/j.cell.2022.06.048Source: DataRank Database

Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases is a research paper published in Cell (2022). On theSindex it has a DataRank of 0. It has been cited 40 times.

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Open Access40 citations

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Enrichment:Funding (15 grants)OA: greenTopics (32)IDs (PubMed, PMC)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Isabella Fraschilla ORCID,Sreehaas Digumarthi,Julie Y. Huang ORCID,Fatemeh Adiliaghdam ORCID,Gracia Bonilla

Live enrichment

PubMed:35952671 PMC:PMC9442451

Canada Foundation for Innovation

Grant: R01AI155662

Canada Foundation for Innovation

Grant: 202695

National Institutes of Health

Grant: R01DK119996

NIDDK NIH HHS

Grant: F31 DK127518

NIDDK NIH HHS

Grant: P30 DK040561

Canada Foundation for Innovation

Grant: 218944

NIDDK NIH HHS

Grant: P30 DK043351

Canada Foundation for Innovation

Grant: 20415

Canadian Institutes of Health Research

Grant: unidentified

unidentified

Harvard Stem Cell Institute

Massachusetts Institute of Technology

Canadian Institutes of Health Research

University of Massachusetts Medical School

University of California Berkeley

Massachusetts General Hospital

greenLicense: Elsevier Non-Commercial

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9442451

https://doi.org/10.1016/j.cell.2022.06.048

https://pubmed.ncbi.nlm.nih.gov/35952671

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

MacrophagesAnimalsHumansMiceCrohn DiseaseAntigens, NuclearTranscription FactorsProteomicsGene Expression RegulationEpigenesis, Genetic

Keywords

MacrophagesTopoisomerasebromodomainchromatinInflammatory Bowel DiseasePhdCrohn’s DiseaseEpigenetic ReaderSp140Speckled ProteinProteomicsAntigens, NuclearEpigenesis, GeneticMiceCrohn DiseaseGene Expression RegulationAnimalsHumansTranscription Factors

Sustainable Development Goals

SDG 3: 3. Good health

Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases

FAIR Checklist

Authors (15)

Funding (15 grants)

Open Access

Topics

Annotations (Europe PMC)