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Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice

Cell(2025)10.1016/j.cell.2025.01.031Source: DataRank Database

Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice is a research paper published in Cell (2025). On theSindex it has a DataRank of 0. It has been cited 54 times.

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Open Access54 citations

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Enrichment:Funding (8 grants)Impact (FWCI 21.98)OA: hybridTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (19)

Shasha Zhang ORCID,Peter Langfelder ORCID,Lalini Ramanathan ORCID,Fuying Gao ORCID,Mary Plascencia

Live enrichment

PubMed:39938516 PMC:PMC11972609 OpenAlex:https://openalex.org/W4407369212

National Institute of Neurological Disorders and Stroke

Grant: R01NS113612

NHGRI NIH HHS

Grant: T32 HG002536

Hereditary Disease Foundation

National Institutes of Health

Jackson Laboratory

University of California, Los Angeles

University of California, Davis

CHDI Foundation Los Angeles

FWCI

21.98

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.cell.2025.01.031

publisherhttps://doi.org/10.1016/j.cell.2025.01.031

publisherhttps://api.elsevier.com/content/article/PII:S009286742500100X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S009286742500100X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39938516

Fields of Study

RNA Research and SplicingGenetic factors in colorectal cancerGenetic Neurodegenerative Diseases

MeSH Terms

MutL Protein Homolog 1Huntingtin ProteinMutS Homolog 3 ProteinAnimalsDisease Models, AnimalDNA-Binding ProteinsHumansHuntington DiseaseMaleNeuronsMice, KnockoutTrinucleotide Repeat ExpansionMiceMutS Homolog 2 ProteinDNA Mismatch RepairGenome-Wide Association Study

Keywords

BiologyPathogenesisGeneGeneticsSet (abstract data type)Cell biologyImmunologyNeuronsCortexThresholdMismatch repairStriatumrateAggregatehuntingtinHuntington's diseasechromatinRna-seqSelective VulnerabilityMLH1MSH2Cag RepeatRepeat ExpansionAtac-seqMsh3Pms1Repeat Instability