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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

Cell(2025)10.1016/j.cell.2025.06.018Source: DataRank Database

Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy is a research paper published in Cell (2025). On theSindex it has a DataRank of 0.633. It has been cited 67 times.

N/A

0.633DataRank · unranked

Scored on demand from live citation data

Open Access67 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (31 grants)Impact (FWCI 32.83)OA: greenTopics (50)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.633

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (37)

Nathaniel Willis ORCID,Tingting Duan ORCID,Amanda Lee ORCID,Yue Zhang ORCID,K.J. Dhanaraj ORCID

Live enrichment

PubMed:40639377 OpenAlex:https://openalex.org/W4412363415

National Computational Infrastructure

Grant: 21CA259636

National Computational Infrastructure

Grant: 01CA293654

National Heart, Lung, and Blood Institute

Grant: R01HL160747

National Heart, Lung, and Blood Institute

Grant: R01HL162658

National Heart, Lung, and Blood Institute

Grant: T32DK007665

National Institutes of Health

Grant: F31CA290756

National Institutes of Health

Grant: NIH - T32 CA082084

National Institutes of Health

Grant: F32CA284780

National Institutes of Health

Grant: P50CA254865

Johnson Cancer Research Center, Kansas State University

Grant: U01CA272541

Johnson Cancer Research Center, Kansas State University

Grant: R01CA253329

National Cancer Institute

Grant: R01CA293654

National Cancer Institute

Grant: R21CA259636

National Institute of Allergy and Infectious Diseases

Grant: P20GM103418

National Institute of Allergy and Infectious Diseases

Grant: DP2AI164325

National Institute of Allergy and Infectious Diseases

Grant: S10OD023402

National Institute of Allergy and Infectious Diseases

Grant: S10OD032141

NIDDK

Grant: R01DK130897

Burroughs Wellcome Fund

Grant: 1017880

United States-Israel Binational Science Foundation

Grant: P30CA047904

United States-Israel Binational Science Foundation

Grant: 2021025

United States-Israel Binational Science Foundation

Grant: R21AI163721

United States-Israel Binational Science Foundation

Grant: R01AI168478

NIAID NIH HHS

Grant: R21 AI188307

NCI NIH HHS

Grant: T32 CA082084

NIAID NIH HHS

Grant: R01 AI118807

NIDDK NIH HHS

Grant: R01 DK138912

NCI NIH HHS

Grant: U01 CA268806

University of Pittsburgh

Melanoma Research Alliance

Universität Wien

FWCI

32.83

Citation Percentile

1.0%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12258965/

publisherhttps://api.elsevier.com/content/article/PII:S0092867425006841?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867425006841?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cell.2025.06.018

Fields of Study

Cancer Immunotherapy and BiomarkersImmune Cell Function and InteractionGut microbiota and healthAnimalsGastrointestinal MicrobiomeMiceImmunotherapyHumansCD8-Positive T-LymphocytesMice, Inbred C57BLImmune Checkpoint InhibitorsMelanomaFormatesPhysical Conditioning, AnimalCell Line, TumorFemale

MeSH Terms

Gastrointestinal MicrobiomeImmune Checkpoint InhibitorsAnimalsFemaleFormatesHumansImmunotherapyMelanomaMice, Inbred C57BLPhysical Conditioning, AnimalCD8-Positive T-LymphocytesCell Line, TumorMice

Keywords

BiologyMelanomaImmune systemImmunityIn vivoImmunotherapyCytotoxic T cellImmunologyCancer researchMetaboliteCD8In vitroBiochemistryExerciseMicrobiotaNRF2FormateCd8 T CellsFmtImmune Checkpoint InhibitorMicrobiota Metabolite

Sustainable Development Goals

SDG 0: Good health and well-being