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Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV

Cell(2025)10.1016/j.cell.2025.08.024Source: DataRank Database

Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV is a research paper published in Cell (2025). On theSindex it has a DataRank of 0. It has been cited 12 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 7.74)OA: greenTopics (31)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (29)

Leah Froehle ORCID,Alexandra N Pipkin,Heeva Baharlou ORCID,Alice H. Linder ORCID,Palak Shah

Live enrichment

PubMed:40939591 PMC:PMC12641501 OpenAlex:https://openalex.org/W4414122316

National Institutes of Health

Grant: 1K99DK136365

National Institutes of Health

Grant: 1R01DK126545

National Institute of Diabetes and Digestive and Kidney Diseases Division of Diabetes Endocrinology and Metabolic Diseases

Grant: 1R01DK133919

NIDDK NIH HHS

Grant: K99 DK136365

NIDDK NIH HHS

Grant: R01 DK126545

NIDDK NIH HHS

Grant: R01 DK133919

NIAID NIH HHS

Grant: U54 AI170856

National Institute on Drug Abuse

National Institute of Allergy and Infectious Diseases Division of Microbiology and Infectious Diseases

Ragon Institute of MGH, MIT and Harvard

FWCI

7.74

Citation Percentile

1.0%

Citation Trend

2025

2026

greenLicense: http://creativecommons.org/licenses/by-nc/4.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12641501/

publisherhttps://api.elsevier.com/content/article/PII:S0092867425009791?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867425009791?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cell.2025.08.024

Fields of Study

HIV Research and TreatmentHIV-related health complications and treatmentsImmune Cell Function and Interaction

MeSH Terms

ColonEpithelial CellsFatty AcidsFemaleHumansIntestinal MucosaMaleMiddle AgedHIV InfectionsApoptosisCD8-Positive T-LymphocytesPPAR gammaLipid Droplets

Keywords

IntracellularDownregulation and upregulationApoptosisIntestinal epitheliumIntestinal mucosaIntestinal DisorderLipid metabolismTight junctionDiseaseHIVIntestinal epithelial cellsImmunometabolismGut Barrier IntegrityImmune-epithelial InteractionTissue Resident Cd8+t Cells