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Hepatic adaptation to chronic metabolic stress primes tumorigenesis

Cell(2025)10.1016/j.cell.2025.11.031Source: DataRank Database

Hepatic adaptation to chronic metabolic stress primes tumorigenesis is a research paper published in Cell (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (22 grants)Impact (FWCI 3.17)OA: hybridTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (4)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (34)

Jessica E.S. Shay ORCID,Marc S. Sherman ORCID,Adam J. Rubin ORCID,Benjamin E. Mead ORCID,Tyler T. Dao ORCID

Live enrichment

PubMed:41435820 PMC:PMC12795325 OpenAlex:https://openalex.org/W7116700970

NIDDK NIH HHS

Grant: K08 DK139370

NIDDK NIH HHS

Grant: P30 DK120531

NIDDK NIH HHS

Grant: F32 DK128872

NCI NIH HHS

Grant: R01 CA245314

NIDDK NIH HHS

Grant: R01 DK135271

NIDDK NIH HHS

Grant: R01 DK062277

NIDA NIH HHS

Grant: DP1 DA053731

NIH HHS

Grant: R24 OD035402

NIDDK NIH HHS

Grant: R01 DK105198

NIH HHS

Grant: R24 OD017870

NIGMS NIH HHS

Grant: T32 GM144273

NCI NIH HHS

Grant: P30 CA014051

NIDDK NIH HHS

Grant: P30 DK040561

NIDDK NIH HHS

Grant: R01 DK090311

NCI NIH HHS

Grant: K08 CA277011

NIDDK NIH HHS

Grant: R01 DK135270

NIDDK NIH HHS

Grant: T32 DK007191

Massachusetts Institute of Technology Koch Institute for Integrative Cancer Research

National Science Foundation

AGA Research Foundation

National Institutes of Health

Hertz Foundation

FWCI

3.17

Citation Percentile

0.9%

Citation Trend

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.cell.2025.11.031

publisherhttps://doi.org/10.1016/j.cell.2025.11.031

publisherhttps://api.elsevier.com/content/article/PII:S0092867425013662?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867425013662?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41435820

Fields of Study

Single-cell and spatial transcriptomicsCancer Cells and MetastasisLiver physiology and pathologyHumansHepatocytesAnimalsCarcinogenesisStress, PhysiologicalLiverMiceMaleLiver NeoplasmsSingle-Cell AnalysisAdaptation, PhysiologicalNon-alcoholic Fatty Liver DiseaseCell ProliferationMice, Inbred C57BLTranscriptome

MeSH Terms

Adaptation, PhysiologicalAnimalsHumansLiverLiver NeoplasmsMaleMice, Inbred C57BLStress, PhysiologicalHepatocytesCell ProliferationMiceSingle-Cell AnalysisTranscriptomeCarcinogenesisNon-alcoholic Fatty Liver Disease

Keywords

HepatocyteCarcinogenesisChronic stressAdaptation (eye)TranscriptomeFunction (biology)SteatohepatitisInflammationMicroarray analysis techniquesLiverMetabolismSingle-cell GenomicsTissue MemoryGenetic PerturbationEpigenetic PrimingComputational Methods DevelopmentChronic Stress Response

Hepatic adaptation to chronic metabolic stress primes tumorigenesis

FAIR Checklist

Authors (34)

Funding (22 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)