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CD4+ T cells engineered with FVIII-CAR and murine Foxp3 suppress anti-factor VIII immune responses in hemophilia a mice

Cellular Immunology(2020)10.1016/j.cellimm.2020.104216Source: DataRank Database

CD4+ T cells engineered with FVIII-CAR and murine Foxp3 suppress anti-factor VIII immune responses in hemophilia a mice is a research paper published in Cellular Immunology (2020). On theSindex it has a DataRank of 0. It has been cited 34 times.

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Open Access34 citations

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Enrichment:Funding (6 grants)OA: greenTopics (26)IDs (PubMed, PMC)Annotations (1)

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Reusable (0/3)

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Authors (6)

Alex C. Chen,Meghan J. Lyle,Chun‐Yu Chen ORCID,Chao-Lien Liu ORCID,Carol H. Miao ORCID

Live enrichment

PubMed:32987195 PMC:PMC7655680

NHLBI NIH HHS

Grant: R01 HL123326

NHLBI NIH HHS

Grant: U54 HL142019

NIAID NIH HHS

Grant: U01 AI101990

NHLBI NIH HHS

Grant: R01 HL151077

NHLBI NIH HHS

Grant: R01 HL134321

National Heart, Lung, and Blood Institute

greenLicense: https://www.elsevier.com/legal/tdmrep-license

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7655680

publisherhttps://api.elsevier.com/content/article/PII:S0008874920303762?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0008874920303762?httpAccept=text/plain

MeSH Terms

CD4-Positive T-LymphocytesAnimalsMice, Inbred C57BLHumansMiceHemophilia AFactor VIIIAntibodies, MonoclonalImmunotherapy, AdoptiveImmune ToleranceMaleT-Lymphocytes, RegulatoryForkhead Transcription FactorsAntibodies, NeutralizingHEK293 CellsGenetic TherapyReceptors, Chimeric Antigen

Keywords

Antibody responseFactor VIIIRegulatory T cellsHemophilia AAdoptive Cell TherapyChimeric Antigen ReceptorTolerance InductionCar-tregsAnti-factor Viii Inhibitors