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The membrane proximal proline-rich region and correct order of C-terminal tyrosines on the adaptor protein LAT are required for TCR-mediated signaling and downstream functions

Cellular Signalling(2020)10.1016/j.cellsig.2020.109790Source: DataRank Database

The membrane proximal proline-rich region and correct order of C-terminal tyrosines on the adaptor protein LAT are required for TCR-mediated signaling and downstream functions is a research paper published in Cellular Signalling (2020). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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Enrichment:Funding (6 grants)Impact (FWCI 0.07)OA: greenTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Tomye Ollinger,Jon C. D. Houtman ORCID,Mikaela M. Tremblay ORCID

Live enrichment

PubMed:32979494 PMC:PMC7669716 OpenAlex:https://openalex.org/W3088789642

NIAID NIH HHS

Grant: R56 AI126493

NCI NIH HHS

Grant: P30 CA086862

National Institutes of Health

Grant: 1R56AI126493-01A1

The role of HCV RNA-targeted phosphatase PTPRE in T cell activation

National Institutes of Health

Grant: 1P30CA086862-01

Core--Clinical trials support group

University of Iowa

National Institutes of Health

FWCI

0.07

Citation Percentile

0.4%

Citation Trend

2021

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7669716

journalhttps://doi.org/10.1016/j.cellsig.2020.109790

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32979494

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669716

Fields of Study

T-cell and B-cell ImmunologyReceptor Mechanisms and SignalingImmune Cell Function and Interaction0301 basic medicine0303 health sciences03 medical and health sciencesAdaptor Proteins, Signal TransducingHumansJurkat CellsLymphocyte ActivationMembrane ProteinsMultiprotein ComplexesProtein BindingProtein DomainsReceptors, Antigen, T-CellSignal Transduction

MeSH Terms

Protein DomainsHumansLymphocyte ActivationMembrane ProteinsProtein BindingReceptors, Antigen, T-CellSignal TransductionJurkat CellsMultiprotein ComplexesAdaptor Proteins, Signal Transducing

Keywords

T-cell receptorSignal transducing adaptor proteinCell biologyJurkat cellsBiologySignal transductionT cellGeneticsImmune systemT cellsTCRLATDomain OrderStructure/function StudyProtein DomainsMultiprotein ComplexesReceptors, Antigen, T-CellHumansMembrane ProteinsLymphocyte ActivationAdaptor Proteins, Signal TransducingProtein Binding

The membrane proximal proline-rich region and correct order of C-terminal tyrosines on the adaptor protein LAT are required for TCR-mediated signaling and downstream functions

FAIR Checklist

Authors (3)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)