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High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis

Cell Reports(2020)10.1016/j.celrep.2020.01.059Source: DataRank Database

High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis is a research paper published in Cell Reports (2020). On theSindex it has a DataRank of 0. It has been cited 30 times.

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Open Access30 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 1.97)OA: goldTopics (120)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Manash K. Paul ORCID,Carla J. Pantoja ORCID,Bharti Bisht ORCID,Luisa K. Meneses ORCID,Preethi Vijayaraj ORCID

Live enrichment

PubMed:32075752 PMC:PMC7050206 OpenAlex:https://openalex.org/W3008372963

NCI NIH HHS

Grant: R01 CA208303

NCI NIH HHS

Grant: T32 CA009056

NCI NIH HHS

Grant: P30 CA016042

NCATS NIH HHS

Grant: UL1 TR000124

NIGMS NIH HHS

Grant: R25 GM055052

NCIRD CDC HHS

Grant: U66 IP000597

NCI NIH HHS

Grant: F31 CA239655

NIGMS NIH HHS

Grant: T32 GM008042

NIGMS NIH HHS

Grant: T34 GM008563

National Institutes of Health

Grant: 2R25GM055052-18

UCLA Maximizing Student Development (MSD) Program

National Institutes of Health

Grant: 5R01CA208303-03

Developing a targeted chemoprevention strategy for Non-Small Cell Lung Cancer

National Institutes of Health

Grant: 5F31CA239655-02

Evaluating the Role and Regulation of Wnt Signaling in Proximal Airway Homeostasis and Injury Repair

National Institutes of Health

Grant: 5T32CA009056-38

Tumor Cell Biology Training Program

National Institutes of Health

Grant: 5T32GM008042-27

Medical Scientist Training Program

National Institutes of Health

Grant: 5UL1TR000124-04

UCLA Clinical and Translational Science Institute

National Institutes of Health

Tobacco-Related Disease Research Program

Jonsson Comprehensive Cancer Center

FWCI

1.97

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: CC BY NC ND

journalhttp://www.cell.com/article/S221112472030084X/pdf

publisherhttp://www.cell.com/article/S221112472030084X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S221112472030084X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S221112472030084X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2020.01.059

Fields of Study

Neonatal Respiratory Health ResearchEpigenetics and DNA MethylationWnt/β-catenin signaling in development and cancer0301 basic medicine03 medical and health sciencesAnimalsBronchiCell DifferentiationDrug Evaluation, PreclinicalFemaleHigh-Throughput Screening AssaysHomeostasisHumansLungMaleMiceMice, Inbred C57BLPrecancerous ConditionsSmall Molecule LibrariesStem CellsTransfectionWnt ProteinsWnt Signaling Pathwaybeta Catenin

MeSH Terms

AnimalsBronchiCell DifferentiationDrug Evaluation, PreclinicalFemaleHomeostasisHumansLungMaleMice, Inbred C57BLPrecancerous ConditionsStem CellsTransfectionWnt Proteinsbeta CateninMiceSmall Molecule LibrariesHigh-Throughput Screening AssaysWnt Signaling Pathway

Keywords

Wnt signaling pathwayCell biologyBiologyHomeostasisStem cellCancer researchBeta-cateninSignal transductionLungWntDrug ScreenPremalignancyAirway Stem CellMaleHomeostasis (mesh)Inbred C57BL (mesh)High-Throughput Screening Assays (mesh)Medical PhysiologyDrug Evaluation, PreclinicalWnt Proteins (mesh)Regenerative MedicineInbred C57BLLung (rcdc)Regenerative Medicine (rcdc)MiceWnt Signaling Pathway (mesh)31 Biological sciences (for-2020)Animals (mesh)Transfection (mesh)Biology (General)Male (mesh)beta CateninCancerStem Cells (mesh)Cancer (rcdc)Humans (mesh)Stem CellsLung CancerMice (mesh)Cell DifferentiationBiological SciencesPreclinical1116 Medical Physiology (for)Small Molecule Libraries (mesh)5.1 PharmaceuticalsLung Cancer (rcdc)Femalebeta Catenin (mesh)570QH301-705.51.1 Normal biological development and functioning0601 Biochemistry and Cell Biology (for)610Cell Differentiation (mesh)BronchiTransfectionArticleSmall Molecule Libraries5.1 Pharmaceuticals (hrcs-rac)AnimalsHumansPreclinical (mesh)1.1 Normal biological development and functioning (hrcs-rac)Bronchi (mesh)Precancerous Conditions (mesh)Cancer (hrcs-hc)Stem Cell ResearchLung (mesh)Stem Cell Research (rcdc)3101 Biochemistry and Cell Biology (for-2020)High-Throughput Screening AssaysMice, Inbred C57BLWnt ProteinsFemale (mesh)Drug EvaluationBiochemistry and Cell BiologyPrecancerous Conditions

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being