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The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis

Cell Reports(2020)10.1016/j.celrep.2020.02.098Source: DataRank Database

The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis is a research paper published in Cell Reports (2020). On theSindex it has a DataRank of 0. It has been cited 48 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access48 citations

Cite:

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (19 grants)Impact (FWCI 5.31)OA: goldTopics (70)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (20)

Carolina Ferreira ORCID,Diana Moreira ORCID,George Eduardo Gabriel Kluck ORCID,Ana Margarida Barbosa ORCID,Egídio Torrado ORCID

Live enrichment

PubMed:32209468 OpenAlex:https://openalex.org/W3013534036

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa

Grant: AAC 01/SAICT/2016

Fundação para a Ciência e a Tecnologia

Grant: IF/01147/2013

Fundação para a Ciência e a Tecnologia

Grant: IF/00735/2014

Fundação para a Ciência e a Tecnologia

Grant: SFRH/BD/120371/2016

Microbiota regulation of cancer immune surveillance

Fundação para a Ciência e a Tecnologia

Grant: SFRH/BD/120127/2016

Dissecting the immunometabolic crosstalk of IL-17A/F-induced macrophage reprogramming during infection

Fundação para a Ciência e a Tecnologia

Grant: SFRH/BPD/96176/2013

THE ROLE OF INFLAMMASOME ACTIVATION IN HOST IMMUNITY TO FUNGAL INFECTION - The inflammasome-microbiota interplay in antifungal immunity

Fundação para a Ciência e a Tecnologia

Grant: PD/BDE/127830/2016

Untitled

Fundação para a Ciência e a Tecnologia

Grant: SFRH/BPD/111100/2015

Carboxydotrophs for alkane production: from CO/CO2 to fuel

Fundação para a Ciência e a Tecnologia

Grant: IF/01390/2014

Fundação para a Ciência e a Tecnologia

Grant: IF/00021/2014

Department of Biotechnology, Ministry of Science and Technology, India

Grant: BT/In/Infect-eRA/33/BS/2016-2017

European Regional Development Fund

Grant: LISBOA-01-0145-FEDER-007660

NIAID NIH HHS

Grant: P30 AI036219

National Institutes of Health

Grant: 5P30AI036219-20

Ugandan Laboratory Core

Canada Research Chairs

Case Western Reserve University

National Institutes of Health

Seventh Framework Programme

Foundation for the National Institutes of Health

FWCI

5.31

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.cell.com/article/S2211124720302722/pdf

publisherhttp://www.cell.com/article/S2211124720302722/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124720302722?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124720302722?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2020.02.098

Fields of Study

Research on Leishmaniasis StudiesPancreatitis Pathology and TreatmentLysosomal Storage Disorders Research0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

AnimalsDisease SusceptibilityHumansLeishmania donovaniLeishmaniasis, VisceralLipidsMacrophagesMembrane ProteinsMice, Inbred BALB CMice, Inbred C57BLGenetic VariationSignal TransductionUp-RegulationMyeloid CellsMitochondrial ProteinsLipogenesisSterol Regulatory Element Binding Protein 1Hypoxia-Inducible Factor 1, alpha SubunitTOR Serine-Threonine KinasesDisease Resistance

Keywords

Leishmania donovaniBiologyLipogenesisLipid metabolismCell biologyInnate immune systemMyeloidSterol regulatory element-binding proteinPI3K/AKT/mTOR pathwaymTORC2Immune systemCancer researchImmunologyTranscription factormTORC1Signal transductionBiochemistryGeneLeishmaniasisVisceral leishmaniasisMacrophagesHIF-1αAcetateMyeloid CellsSrebp-1cFasnQH301-705.5Mitochondrial ProteinsAnimalsHumansBiology (General)Disease ResistanceMice, Inbred BALB CTOR Serine-Threonine KinasesGenetic VariationMembrane ProteinsHypoxia-Inducible Factor 1, alpha SubunitLipidsUp-Regulation[SDV] Life Sciences [q-bio]Mice, Inbred C57BLLeishmaniasis, VisceralDisease SusceptibilitySterol Regulatory Element Binding Protein 1

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being