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Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

Cell Reports(2020)10.1016/j.celrep.2020.107616Source: DataRank Database

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo is a research paper published in Cell Reports (2020). On theSindex it has a DataRank of 0. It has been cited 48 times.

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Open Access48 citations

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Enrichment:Funding (26 grants)OA: goldTopics (37)IDs (PubMed, PMC)Annotations (1)

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Authors (23)

Zachary T. McEachin ORCID,Jeannie Chew ORCID,Alexander R. Burch ORCID,Karen Jansen‐West ORCID,Jimei Tong

Live enrichment

PubMed:32375043 PMC:PMC7480900

NINDS NIH HHS

Grant: R01 NS088689

NINDS NIH HHS

Grant: P30 NS055077

NIEHS NIH HHS

Grant: R01 ES020395

NINDS NIH HHS

Grant: R01 NS091749

NINDS NIH HHS

Grant: R21 NS084528

NINDS NIH HHS

Grant: R35 NS097263

NINDS NIH HHS

Grant: P01 NS084974

NIA NIH HHS

Grant: RF1 AG062077

NIA NIH HHS

Grant: RF1 AG056318

NINDS NIH HHS

Grant: P01 NS099114

NINDS NIH HHS

Grant: R35 NS097273

National Institutes of Health

Grant: 5P30NS055077-02

Emory Neuroscience NINDS Core Facilities

National Institutes of Health

Grant: 1R21NS084528-01

RNA foci in C9FTD/ALS

National Institutes of Health

Grant: 5P01NS084974-07

Pathobiology of Neurodegeneration in C9ORF72 repeat expansion

National Institutes of Health

Grant: 4R01ES020395-05

Stress Granules and the Biology of TDP-43

National Institutes of Health

Grant: 1R35NS097273-01

Expanding insights into FTD disease mechanisms

National Institutes of Health

Grant: 7R01NS091749-03

RNA Processing Defects in SMA and Their Contribution to the Disease Phenotype

National Institutes of Health

Grant: 1R01NS088689-01

Silencing C9or72 with rAAV Mediated RNAi

National Institutes of Health

Grant: 3R35NS097263-06S1

Innovating Yeast and Human Genetics Approaches to Define Mechanisms of Neurodegenerative Disease

National Institutes of Health

Grant: 1P01NS099114-01

Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways

Muscular Dystrophy Association

National Institute of Environmental Health Sciences

U.S. Department of Defense

Amyotrophic Lateral Sclerosis Association

National Institute of Neurological Disorders and Stroke

Robert Packard Center for ALS Research, Johns Hopkins University

goldLicense: CC BY NC ND

publisherhttp://www.cell.com/article/S2211124720305659/pdf

repositoryhttps://doaj.org/article/a1385bc8f994442d9c1094bb8a16c0d4

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7480900

https://doi.org/10.1016/j.celrep.2020.107616

https://pubmed.ncbi.nlm.nih.gov/32375043

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

NeuronsInclusion BodiesAnimalsHumansMiceAmyotrophic Lateral SclerosisNuclear ProteinsRNADNA Repeat ExpansionFrontotemporal DementiaC9orf72 Protein

Keywords

MouseALSTdp-43C9orf72FtdRan TranslationRna FociPoly(pr)Sca36Poly(gp)Inclusion BodiesNeuronsDNA Repeat ExpansionC9orf72 ProteinQH301-705.5Amyotrophic Lateral SclerosisNuclear ProteinsMiceFrontotemporal DementiaAnimalsHumansRNABiology (General)