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Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

Cell Reports(2020)10.1016/j.celrep.2020.107711Source: DataRank Database

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells is a research paper published in Cell Reports (2020). On theSindex it has a DataRank of 0. It has been cited 119 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access119 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (27 grants)Impact (FWCI 15.26)OA: goldTopics (94)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (23)

Alexandra Collin de l’Hortet ORCID,Yang Wang ORCID,Kan Handa,Jorge Guzman‐Lepe,Kentaro Matsubara ORCID

Live enrichment

PubMed:32492423 PMC:PMC7734598 OpenAlex:https://openalex.org/W3032600724

Université Pierre et Marie Curie

Grant: P30CA047904

American Liver Foundation

Grant: PCT/US2018/018032

American Liver Foundation

Grant: WO/2015/168254

American Liver Foundation

Grant: WO/2011/002926

National Institutes of Health

Grant: HSN276201200017C

National Institutes of Health

Grant: DK117881

National Institutes of Health

Grant: DK103645

National Institutes of Health

Grant: DK107697

National Institutes of Health

Grant: DK119973

National Institutes of Health

Grant: TR002383

National Institutes of Health

Grant: P30DK120531

National Institutes of Health

Grant: DK099257

NIDDK NIH HHS

Grant: R01 DK099257

NIDDK NIH HHS

Grant: R01 DK103645

NIDDK NIH HHS

Grant: UH3 DK119973

NIDDK NIH HHS

Grant: R01 DK107697

NIDDK NIH HHS

Grant: P01 DK096990

NIDDK NIH HHS

Grant: R01 DK117881

NIDDK NIH HHS

Grant: UG3 DK119973

NCATS NIH HHS

Grant: U01 TR002383

National Institutes of Health

Grant: 5R01DK099257-02

Mini-Livers Derived from Human IPS Cells for Modeling Steatosis and Therapy

National Institutes of Health

Grant: 1P30DK120531-01

Pittsburgh Liver Research Center

National Institutes of Health

Grant: 3P30CA047904-07S1

CANCER CENTER SUPPORT GRANT

National Institutes of Health

Grant: 5UH3DK119973-04

Human Microphysiology Systems Disease Model of Type 2 Diabetes Starting with Liver and pancreatic Islets

National Institutes of Health

Grant: 7P01DK096990-05

New therapies for liver fibrosis and hyperproliferation in alpha1-AT deficiency

National Institutes of Health

Grant: 5R01DK117881-04

Applying a Human Liver Microphysiology System to Develop Therapeutic Strategies for Non-Alcoholic Fatty Liver Disease (NAFLD)

University of Pittsburgh

FWCI

15.26

Citation Percentile

1.0%

Influential Citations

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S2211124720306884/pdf

GOLDhttp://www.cell.com/article/S2211124720306884/pdf

publisherhttp://www.cell.com/article/S2211124720306884/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124720306884?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124720306884?httpAccept=text/plain

Fields of Study

Tissue Engineering and Regenerative MedicineLiver physiology and pathologyPluripotent Stem Cells ResearchBiologyMedicineEngineering03 medical and health sciences0303 health sciencesActivinsAnimalsBone Morphogenetic Protein 4Cell DifferentiationCells, CulturedCellular ReprogrammingFetusFibroblast Growth Factor 2FibroblastsHepatocytesHumansImmunocompromised HostInduced Pluripotent Stem CellsMaleRatsRats, Sprague-DawleyTissue EngineeringTissue ScaffoldsTranscription Factors

MeSH Terms

AnimalsCell DifferentiationCells, CulturedFetusFibroblastsHumansMaleTranscription FactorsFibroblast Growth Factor 2Immunocompromised HostRats, Sprague-DawleyHepatocytesTissue EngineeringActivinsRatsTissue ScaffoldsBone Morphogenetic Protein 4Induced Pluripotent Stem CellsCellular Reprogramming

Keywords

Induced pluripotent stem cellDecellularizationTransplantationStem cellCell biologyBiologyHuman liverParenchymaChimera (genetics)PathologyCancer researchEmbryonic stem cellIn vitroMedicineInternal medicineBiochemistryExtracellular matrixHuman Ips CellsLiver MaturationBioengineered Human LiverHuman Ips-biliary CellsHuman Ips-endothelial CellsHuman Ips-hepatocytesMini Human LiverOrgan-microenvironmentMaleQH301-705.5Induced Pluripotent Stem CellsBone Morphogenetic Protein 4Rats, Sprague-DawleyImmunocompromised HostFetushttps://purl.org/becyt/ford/3.1AnimalsHumanshttps://purl.org/becyt/ford/3Biology (General)Cells, CulturedTissue EngineeringTissue ScaffoldsCell DifferentiationFibroblastsCellular ReprogrammingActivinsRatsHepatocytesFibroblast Growth Factor 2Transcription Factors

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Related Papers (2)

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N/A

3.7DataRank · unranked

Nature Materials(2020)

co-cited

10.1038/s41563-020-00853-9

Regional Differences in Human Biliary Tissues and Corresponding In Vitro–Derived Organoids

Hepatology(2020)

co-cited

10.1002/hep.31252

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

FAIR Checklist

Authors (23)

Funding (27 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)

Related Papers (2)