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Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts

Cell Reports(2020)10.1016/j.celrep.2020.107716Source: DataRank Database

Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts is a research paper published in Cell Reports (2020). On theSindex it has a DataRank of 1.4. It has been cited 68 times, with 37 citing works in its 1-hop citation network.

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1.4DataRank · unranked

Scored on demand from live citation data

Open Access68 citations · 37 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (37 grants)OA: goldTopics (74)IDs (PubMed, PMC)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 46%Citation Network 54%

Base Score Contribution

0.635

From this paper's citation signal

Citation Network Contribution

0.742

From 29 citing papers with measurable signal

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Authors (45)

Chris Chatzinakos ORCID,Michael S. Breen ORCID,Jakob Hartmann ORCID,Torsten Klengel ORCID,Ana C. da Silva Almeida

Live enrichment

PubMed:32492425 PMC:PMC7359754

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: P30DK20595

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: U01MH109536

Medical Research and Materiel Command

Grant: R01MH106595

Harvard University

Grant: R01MH118278

One Mind

Grant: U01MH109539

National Center for Advancing Translational Sciences

Grant: KL2TR002542

National Center for Advancing Translational Sciences

Grant: UL1TR002541

NIMH NIH HHS

Grant: R01 MH107666

NIMH NIH HHS

Grant: P50 MH115874

NIMH NIH HHS

Grant: R01 MH101820

NIMH NIH HHS

Grant: R01 MH117292

NIDDK NIH HHS

Grant: P30 DK020595

NIMH NIH HHS

Grant: R01 MH124839

NIMH NIH HHS

Grant: R01 MH124847

NIMH NIH HHS

Grant: T32 MH017119

National Institutes of Health

Grant: 5R01MH118278-03

Predicting the multi-omic impact of psychiatric GWAS associations

National Institutes of Health

Grant: 3U01MH109539-04S1

2/7 Psychiatric Genomics Consortium: Finding Actionable Variation

National Institutes of Health

Grant: 3P50MH115874-04S1

Silvio O. Conte Center for Stress Peptide Advanced Research, Education, & Dissemination (SPARED) at McLean Hospital

National Institutes of Health

Grant: 5R01MH106595-02

Psychiatric Genomics Consortium for PTSD

National Institutes of Health

Grant: 3U01MH109536-04S1

3/7 Psychiatric Genomics Consortium: Finding actionable variation

National Institutes of Health

Grant: 2P30DK020595-36

Core B: Molecular Biol. Genetics Core

National Institutes of Health

Grant: 5KL2TR002542-02

Institutional Career Development Core

National Institutes of Health

Grant: 1R01MH101820-01

Harnessing GTEx to Create Transcriptome Knowledge and Inform Disease Biology

National Institutes of Health

Grant: 5UL1TR002541-04

The Harvard Clinical and Translational Science Center

National Institutes of Health

Grant: 1R01MH107666-01

Predicted Gene Expression: High Power, Mechanism, and Direction of Effect

Cohen Veterans Bioscience

Takeda Pharmaceuticals U.S.A.

Beatrice and Samuel A. Seaver Foundation

Sunovion

H. Lundbeck A/S

National Alliance for Research on Schizophrenia and Depression

National Institute of Mental Health

Broad Institute

Brain and Behavior Research Foundation

National Institutes of Health

Harvard Catalyst

McLean Hospital

goldLicense: CC BY NC ND

publisherhttp://www.cell.com/article/S2211124720306938/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124720306938?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124720306938?httpAccept=text/plain

repositoryhttps://escholarship.org/uc/item/5005k6b1

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7359754

Fields of Study

0301 basic medicine0302 clinical medicine03 medical and health sciences

MeSH Terms

Prefrontal CortexLeukocytesAnimalsMice, Inbred C57BLHumansMiceGenetic Predisposition to DiseaseDexamethasoneRibonucleoproteins, Small NuclearRepressor ProteinsRNA, Small InterferingCase-Control StudiesCohort StudiesStress Disorders, Post-TraumaticGene Expression RegulationDown-RegulationRNA InterferenceMilitary PersonnelMaleGene Regulatory Networks

Keywords

BloodSexSplicingGlucocorticoidprefrontal cortexMilitaryPtsdGwasCivilianTranscriptomic ImputationMaleMedical PhysiologyInbred C57BLDexamethasoneCohort StudiesStress Disorders, Post-TraumaticMiceLeukocytesgeneticsGene Regulatory NetworksBiology (General)RNA, Small InterferingStress DisordersPost-Traumatic Stress Disorder (PTSD)Ribonucleoproteins, Small NuclearMental HealthtraumaMilitary PersonnelRibonucleoproteinsNeurologicalRNA InterferenceQH301-705.51.1 Normal biological development and functioning610Down-RegulationSmall InterferingSmall NuclearUnderpinning researchAnimalsHumansGenetic Predisposition to DiseaseNeurosciencesBrain DisordersMice, Inbred C57BLRepressor ProteinsGene Expression RegulationCase-Control StudiesPost-TraumaticRNABiochemistry and Cell BiologyPTSD Working Group of Psychiatric Genomics Consortium

Sustainable Development Goals

SDG 3: 3. Good health