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RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha

Cell Reports(2020)10.1016/j.celrep.2020.107931Source: DataRank Database

RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha is a research paper published in Cell Reports (2020). On theSindex it has a DataRank of 0. It has been cited 15 times.

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Scored on demand from live citation data

Open Access15 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 1.92)OA: goldTopics (93)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Zachary M. Sandusky ORCID,Kimberly M. Stauffer ORCID,Yu Li ORCID,Kelli L. Boyd,George A. O’Doherty ORCID

Live enrichment

PubMed:32697984 PMC:PMC7465694 OpenAlex:https://openalex.org/W3043971596

National Institutes of Health

Grant: CA213201

National Institutes of Health

Grant: AI142040

National Institutes of Health

Grant: DK113423

National Institutes of Health

Grant: AI144196

National Science Foundation

Grant: CHE-1565788

National Science Foundation

Grant: SL0101

NIAID NIH HHS

Grant: R21 AI142040

NIAID NIH HHS

Grant: R03 AI144196

NCI NIH HHS

Grant: R01 CA213201

NIDDK NIH HHS

Grant: R01 DK113423

National Institutes of Health

Grant: 5R01CA213201-05

RSK2 in Estrogen Receptor Positive (ER+) Breast Cancer

National Institutes of Health

Grant: 1R03AI144196-01

Targeted modification of the apramycin 2-deoxystreptamine ring to block aminoglycoside modifying enzyme-based inactivation and enhance potency against multidrug-resistant Gram-negative pathogens

National Institutes of Health

Grant: 5R21AI142040-02

Apramycin scaffold exploration using novel glycochemistry and SAR studies to enhance activity against Acinetobacter baumannii and other multidrug-resistant Gram-negative pathogens

National Institutes of Health

Grant: 5R01DK113423-04

Estrogen Receptor Homeostasis

Eunice Kennedy Shriver National Institute of Child Health and Human Development

FWCI

1.92

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S2211124720309128/pdf

publisherhttp://www.cell.com/article/S2211124720309128/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124720309128?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124720309128?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2020.107931

Fields of Study

Estrogen and related hormone effectsCytokine Signaling Pathways and InteractionsMelanoma and MAPK Pathways0301 basic medicine0303 health sciences03 medical and health sciencesAgingAnimalsBreastEpithelial Cell Adhesion MoleculeEpitheliumEstrogen Receptor alphaEstrogensEstrous CycleExtracellular Signal-Regulated MAP KinasesFemaleHomeostasisHumansMammary Glands, AnimalMice, KnockoutOxidative StressPhosphorylationPhosphoserineProteasome Endopeptidase ComplexProtein BiosynthesisProteolysisRibosomal Protein S6 Kinases, 90-kDaSignal TransductionTranscription, GeneticUterus

MeSH Terms

Epithelial Cell Adhesion MoleculeAgingAnimalsBreastEpitheliumEstrogensFemaleHomeostasisHumansMammary Glands, AnimalPhosphorylationPhosphoserineTranscription, GeneticProtein BiosynthesisUterusSignal TransductionMice, KnockoutOxidative StressEstrous CycleRibosomal Protein S6 Kinases, 90-kDaProteasome Endopeptidase ComplexEstrogen Receptor alphaExtracellular Signal-Regulated MAP KinasesProteolysis

Keywords

EstrogenEstrogen receptorEstrogen receptor alphaHomeostasisEndocrinologyInternal medicineEstrogen receptor betaBiologyEstrous cycleMedicineCancerBreast cancerMammary glandTransgenic miceMAPKERK1/2growth factorsRsk2ErαP90rskP90 Ribosomal S6 KinaseMice, KnockoutAgingProteasome Endopeptidase ComplexEstrogensEpithelial Cell Adhesion MoleculeArticleEpitheliumOxidative StressPhosphoserineMammary Glands, AnimalProtein BiosynthesisProteolysisAnimalsHumansFemaleBreastPhosphorylationExtracellular Signal-Regulated MAP Kinases

Sustainable Development Goals

SDG 0: Good health and well-being