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Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

Cell Reports(2020)10.1016/j.celrep.2020.108286Source: DataRank Database

Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG is a research paper published in Cell Reports (2020). On theSindex it has a DataRank of 0. It has been cited 69 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access69 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 3.21)OA: goldTopics (66)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (33)

Etienne Danis ORCID,Angela M. Pierce ORCID,Krishna Madhavan ORCID,Dong Wang ORCID,Nathan Dahl ORCID

Live enrichment

PubMed:33086074 OpenAlex:https://openalex.org/W3094086985

U.S. Department of Defense

Grant: CA 160704

National Cancer Institute

Grant: P30CA046934

NIH HHS

Grant: S10 OD023485

NIH HHS

Grant: S10 OD027023

FWCI

3.21

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.celrep.2020.108286

publisherhttps://doi.org/10.1016/j.celrep.2020.108286

publisherhttps://api.elsevier.com/content/article/PII:S2211124720312754?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124720312754?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33086074

Fields of Study

Epigenetics and DNA MethylationGenomics and Chromatin DynamicsChromatin Remodeling and CancerAgingAstrocytomaBrain Stem NeoplasmsCell DifferentiationCell Line, TumorCell ProliferationChildChild, PreschoolChromatinDiffuse Intrinsic Pontine GliomaEpigenomicsFemaleGliomaHistonesHumansLysineMaleMutationNeoplasm Recurrence, LocalPolycomb Repressive Complex 1

MeSH Terms

Diffuse Intrinsic Pontine GliomaAgingAstrocytomaCell DifferentiationChildChild, PreschoolChromatinFemaleGliomaHistonesHumansLysineMaleMutationNeoplasm Recurrence, LocalBrain Stem NeoplasmsCell Line, TumorCell ProliferationEpigenomicsPolycomb Repressive Complex 1

Keywords

BMI1EpigenomicsSenescenceCancer researchBiologyChromatinPhenotypeRNA interferenceHistoneCell biologyStem cellGeneticsGene expressionGeneDNA methylationRNABH3 mimeticsDIPGH3K27M mutantH3WTPTC 028RNAi screenSASP

Sustainable Development Goals

SDG 0: Good health and well-being