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A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress

Cell Reports(2020)10.1016/j.celrep.2020.108563Source: DataRank Database

A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress is a research paper published in Cell Reports (2020). On theSindex it has a DataRank of 0. It has been cited 65 times.

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Open Access65 citations

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Enrichment:Funding (5 grants)Impact (FWCI 3.13)OA: goldTopics (67)Linked Datasets (12)DataCite Reuse (12)IDs (PubMed, PMC, OpenAlex)Annotations (1)

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Findable (2/2)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Authors (6)

Sha Sun ORCID,Suhila Appathurai,Arunkumar Sundaram,Rachel Plumb ORCID,Malaiyalam Mariappan ORCID

Live enrichment

PubMed:33378667 PMC:PMC7809255 OpenAlex:https://openalex.org/W3115453032

National Institutes of Health

Grant: R01GM117386

National Institutes of Health

Grant: R21AG056800

National Institutes of Health

Grant: 2xStrep-Sec61\u03B1 HEK293

National Institutes of Health

Grant: 2R01GM117386-06

The interplay between the UPR and protein biogenesis at the ER

National Institutes of Health

Grant: 1R21AG056800-01A1

Retro-proteomics to identify misfolded proteins from the ER and their quality control pathways

FWCI

3.13

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S2211124720315527/pdf

publisherhttp://www.cell.com/article/S2211124720315527/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124720315527?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124720315527?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2020.108563

Fields of Study

Endoplasmic Reticulum Stress and DiseaseRNA regulation and diseaseAutophagy in Disease and Therapy0301 basic medicine03 medical and health sciences

MeSH Terms

SEC Translocation ChannelsX-Box Binding Protein 1Endoplasmic Reticulum Chaperone BiPEndoplasmic ReticulumEndoribonucleasesGene Expression RegulationHeat-Shock ProteinsHumansModels, BiologicalProtein BindingRNA SplicingTranscription FactorsSignal TransductionRNA-Binding ProteinsProtein Serine-Threonine KinasesMolecular ChaperonesMembrane Transport ProteinsProtein Interaction Domains and MotifsProtein MultimerizationGene Knockout TechniquesUnfolded Protein ResponseHEK293 CellsEndoplasmic Reticulum Stress

Keywords

Endoplasmic reticulumUnfolded protein responseXBP1Cell biologyEndoribonucleaseTransloconCalnexinRNA splicingBiologyRNase PChemistryGeneGeneticsCalreticulinRNAChromosomal translocationProtein translocationER stressIre1Sec61 TransloconMembrane Transport ProteinsRNA-Binding ProteinsProtein Serine-Threonine KinasesEndoplasmic Reticulum StressModels, BiologicalArticleGene Knockout TechniquesHEK293 CellsGene Expression RegulationEndoribonucleasesHumansProtein Interaction Domains and MotifsProtein MultimerizationEndoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsSEC Translocation ChannelsMolecular ChaperonesProtein BindingSignal Transduction

Additional file 1 of Activation of ACLY by SEC63 deploys metabolic reprogramming to facilitate hepatocellular carcinoma metastasis upon endoplasmic reticulum stress

10.6084/m9.figshare.22724243.v1figshare

Additional file 1 of Activation of ACLY by SEC63 deploys metabolic reprogramming to facilitate hepatocellular carcinoma metastasis upon endoplasmic reticulum stress

10.6084/m9.figshare.22724243figshare

Additional file 1 of ER Ca2+ overload activates the IRE1α signaling and promotes cell survival

10.6084/m9.figshare.26601682.v1figshare

Additional file 1 of ER Ca2+ overload activates the IRE1α signaling and promotes cell survival

10.6084/m9.figshare.26601682figshare

Additional file 2 of ER Ca2+ overload activates the IRE1α signaling and promotes cell survival

10.6084/m9.figshare.26601685.v1figshare

Additional file 2 of ER Ca2+ overload activates the IRE1α signaling and promotes cell survival

10.6084/m9.figshare.26601685figshare

Additional file 3 of ER Ca2+ overload activates the IRE1α signaling and promotes cell survival

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Additional file 3 of ER Ca2+ overload activates the IRE1α signaling and promotes cell survival