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IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

Cell Reports(2021)10.1016/j.celrep.2021.108891Source: DataRank Database

IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 95 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access95 citations

Cite:

Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (25 grants)Impact (FWCI 4.25)OA: goldTopics (75)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (16)

Yajing Gao ORCID,Igor Dozmorov ORCID,Venkat S. Malladi ORCID,Irene Saha ORCID,Margaret M. McDaniel ORCID

Live enrichment

PubMed:33761354 PMC:PMC8300000 OpenAlex:https://openalex.org/W3138049691

National Institutes of Health

Grant: AI123176

National Institutes of Health

Grant: GM120196

Cancer Prevention and Research Institute of Texas

Grant: R01 AR073228

Cancer Prevention and Research Institute of Texas

Grant: R01 GM055479

Cancer Prevention and Research Institute of Texas

Grant: R01 HG010730

Cancer Prevention and Research Institute of Texas

Grant: R01 NS099068

Cancer Prevention and Research Institute of Texas

Grant: RP150596

National Institute of Allergy and Infectious Diseases

Grant: AI113125

NIAID NIH HHS

Grant: R01 AI113125

NIGMS NIH HHS

Grant: R01 GM120196

NIAID NIH HHS

Grant: R01 AI148276

NIDDK NIH HHS

Grant: R01 DK107502

NIAID NIH HHS

Grant: T32 AI005284

NIAID NIH HHS

Grant: K24 AI150992

NIAID NIH HHS

Grant: R01 AI123176

NCI NIH HHS

Grant: R01 CA231303

National Institutes of Health

Grant: 5R01NS099068-08

Binding of Epstein Barr Virus EBNA2 Unifies Multiple Sclerosis Genetic Mechanisms

National Institutes of Health

Grant: 5R01GM055479-22

Biochemical and Computational Analysis of Notch signal transduction

National Institutes of Health

Grant: 5R01AI123176-02

Innate mechanisms of regulation of memory Th17 cell responses

National Institutes of Health

Grant: 1R01AR073228-01A1

Transcription Factor Genetics in Lupus

National Institutes of Health

Grant: 5R01HG010730-03

Virus-driven human gene misregulation in disease

National Institutes of Health

Grant: 5R01AI113125-06

ROLE OF BCAP IN REGULATING INFLAMMATION AND ADAPTIVE IMMUNITY

National Institutes of Health

Grant: 5R01GM120196-03

Endocytic Trafficking and Cell Signaling in Models of ARC Syndrome

University of Texas Southwestern Medical Center

Cincinnati Children’s Research Foundation

FWCI

4.25

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: CC BY NC ND

journalhttp://www.cell.com/article/S2211124721002059/pdf

publisherhttp://www.cell.com/article/S2211124721002059/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721002059?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721002059?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2021.108891

Fields of Study

Immune Response and InflammationImmune cells in cancerinterferon and immune responses0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

THP-1 CellsBase SequenceCell NucleusChromatinDendritic CellsGene Expression RegulationHumansImmunityInterferonsLipopolysaccharidesMacrophagesMonocytesProtein BindingSignal TransductionChemokinesCell LineageProtein TransportMyeloid CellsInterferon Regulatory Factor-1Toll-Like ReceptorsNucleotide Motifs

Keywords

TLR7IRF1Cell biologyBiologyTranscription factorTLR4IRF8InterferonInterferon regulatory factorsMonocyteRegulation of gene expressionInflammationTranscriptional regulationChromatinInnate immune systemSignal transductionGeneImmunologyToll-like receptorImmune systemGeneticsMacrophagesMonocytesChromatin AccessibilityHuman PbmcsIrf3Interferon-stimulated GenesTlr8Pioneer Transcription FactorLipopolysaccharidesQH301-705.5THP-1 CellsArticleHumansCell LineageMyeloid CellsBiology (General)Nucleotide MotifsCell NucleusBase SequenceImmunityDendritic CellsProtein TransportGene Expression RegulationInterferonsChemokinesInterferon Regulatory Factor-1Protein Binding

Sustainable Development Goals

SDG 0: Good health and well-being

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