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An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein

Cell Reports(2021)10.1016/j.celrep.2021.109189Source: DataRank Database

An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 13 times.

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Open Access13 citations

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Enrichment:Funding (64 grants)Impact (FWCI 0.93)OA: goldTopics (43)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (33)

Alessandro Crimi ORCID,Anne Wiedmer ORCID,Marc Emmenegger ORCID,C. Manzoni ORCID,Sara Bandrés‐Ciga ORCID

Live enrichment

PubMed:34107263 PMC:PMC8207177 OpenAlex:https://openalex.org/W3167728079

European Molecular Biology Organization

Grant: ATLF-815-2014

Wellcome Trust

Grant: 202903/Z/16/Z

University College London

Grant: MR/N008324/1

Using transcriptomics to transform the diagnosis and understanding of inherited adult neurological disorders

European Commission

Grant: G Α -2013-609409

European Commission

Grant: LTFCOFUND2013

European Research Council

Grant: ERC 670958

Human Frontier Science Program

Grant: LT001044/2017

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Grant: 166943

REFRAME - Pathway complexities of protein misfolding in neurodegenerative diseases: a novel approach to risks evaluation and model development

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Grant: 179040

The prion protein in health and disease

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Grant: 183563

PrP and its receptor GPR126: guardians of axomyelinic integrity and druggable targets against demyelinating diseases

U.S. Department of Health and Human Services

Grant: 1ZI Α -NS003154

U.S. Department of Health and Human Services

Grant: Z01-AG000949-02

U.S. Department of Health and Human Services

Grant: Z01-ES101986

Weston Brain Institute

Grant: 18063

UK Research and Innovation

Grant: MR/L012758/1

A flow cytometry facility for ocular regenerative medicine

Medical Research Council

Grant: MR/N026004/1

Understanding the genes for Parkinson's disease

Medical Research Council

Grant: G0901254

Medical Research Council

Grant: MR/L501542/1

Parkinson's UK

Grant: G-1307

Parkinson's UK

Grant: G-0907

European Research Council

Grant: 670958

Function and malfunction of the prion protein

Medical Research Council

Grant: G0701075

Intramural NIH HHS

Grant: Z01 ES101986

Rosetrees

Grant: M733

Medical Research Council

Grant: MR/J004758/1

Medical Research Council

Grant: UKDRI-1009

Medical Research Council

Grant: MR/K01417X/1

Intramural NIH HHS

Grant: Z01 AG000949

Medical Research Council

Grant: G1001253

European Commission

Grant: 609409

Supporting transnational mobility within the European life sciences by cofunding of the EMBO Fellowship Programme

National Institutes of Health

Grant: 1ZIAES101986-05

Prospective studies on Parkinson's disease

Wellcome Trust

Grant: 202903

BRAINEACv2: a resource for the interpretation of genetic variation in multiple regions of the adult human brain

National Institutes of Health

Grant: 1Z01ES101986-03

Prospective studies on Parkinson's disease

National Institutes of Health

Grant: 1ZIANS003154-09

Genetic characterization of atypical parkinsonism

National Institutes of Health

Grant: 1Z01AG000949-01

Genome wide SNP analysis in Neurological disorders

Dolby Family Ventures

National Institute of Environmental Health Sciences

UK Dementia Research Institute

Alzheimer’s Research UK

Biogen

European Research Council

National Institute on Aging

Novartis

Takeda Pharmaceutical Company

UCLH Biomedical Research Centre

University College London Hospitals NHS Foundation Trust

Fundación Séneca

Great Ormond Street Hospital Charity

Tau Consortium

Alzheimer's Association

FP7 People: Marie-Curie Actions

JPB Foundation

Universität Zürich

AbbVie

Cure Alzheimer's Fund

National Institutes of Health

U.S. Department of Justice

Alzheimer's Society

Japan Science and Technology Agency

Michael J. Fox Foundation for Parkinson's Research

NOMIS Stiftung

National Institute of Neurological Disorders and Stroke

Wellcome Trust

FWCI

0.93

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: CC BY NC ND

journalhttp://www.cell.com/article/S2211124721005350/pdf

publisherhttp://www.cell.com/article/S2211124721005350/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721005350?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721005350?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2021.109189

Fields of Study

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and SignalingNerve injury and regeneration0301 basic medicine03 medical and health sciences0303 health sciencesCell CommunicationGenome-Wide Association StudyHumansProtein Interaction Mapsalpha-Synuclein

MeSH Terms

Cell CommunicationHumansalpha-SynucleinGenome-Wide Association StudyProtein Interaction Maps

Keywords

BiologyCellComputational biologyGeneticsCell biologySiRNAα-synucleinGwasHigh-throughput ScreenWeighted Gene Co-expression Network AnalysisItga8Braak HypothesisWeighted Protein-protein Network Interaction Analysis10208 Institute of Neuropathology610 Medicine & healthGenetics and Molecular BiologyCell CommunicationArticle1300 General Biochemistry, Genetics and Molecular BiologyHumansProtein Interaction Maps610 Medicine & health10032 Clinic for Oncology and HematologyGeneral Biochemistryalpha-Synuclein570 Life sciences; biologyGenome-Wide Association Study

Sustainable Development Goals

SDG 3: 3. Good health

An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein

FAIR Checklist

Authors (33)

Funding (64 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)