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Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer

Cell Reports(2021)10.1016/j.celrep.2021.109285Source: DataRank Database

Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 98 times.

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Open Access98 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)OA: goldTopics (24)IDs (PubMed)SDGs (2)

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Authors (22)

Mehdi Chaib ORCID,Laura M. Sipe ORCID,Emily J. Miller ORCID,Bin Teng,Rahul Sharma ORCID

Live enrichment

PubMed:19910364

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01DK127209

Harvard Transdisciplinary Research in Energetics and Cancer Center, Harvard University

Grant: R25CA203650

NIH

Grant: R37CA226969

NIH

Grant: R01CA253329

NIH

Grant: U24CA210988

NIH

Grant: UG1CA233333

NIH

Grant: U01ES019472

National Institutes of Health

Grant: 2R25CA203650-06

Transdisciplinary Research in Energetics and Cancer (TREC) Training Grant

National Institutes of Health

Grant: 3R01CA229164-02S2

Racial Disparity in the Expression of Androgen Receptor Splice Variants (AR-SVs) in Prostate Cancer

National Institutes of Health

Grant: 1U24CA210988-01

RNA sequencing analysis of Cancer

National Institutes of Health

Grant: 5U01ES019472-05

Pregnancy, Obesogenic Environments, and Basal-like Breast Cancer

National Institutes of Health

Grant: 5UG1CA233333-03

UNITS: The UNC / UT National Clinical Trials Network Group Integrated Translational Science Production and Consultation Center

National Institutes of Health

Grant: 5F31CA257388-02

Impact of the Breast Cancer Immune Microenvironment on Racial Disparities and Survivorship

National Institutes of Health

Grant: 5R01CA253329-04

Role of microbial-modulated bile acid receptor signaling in breast cancer

National Institutes of Health

Grant: 5R37CA226969-05

Obesity-driven Metabolic and Molecular Biomarkers of Metformin Response in Endometrial Cancer

goldLicense: CC BY NC ND

publisherhttps://doi.org/10.1016/j.celrep.2021.109285

publisherhttps://api.elsevier.com/content/article/PII:S2211124721006562?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721006562?httpAccept=text/plain

repositoryhttp://europepmc.org/pmc/articles/PMC8574993

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8574993

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

Programmed Cell Death 1 ReceptorBreast NeoplasmsArticleMiceLymphocytes, Tumor-InfiltratingTumor MicroenvironmentAnimalsHumansObesityImmune Checkpoint InhibitorsImmunosuppression TherapyMacrophagesMyeloid-Derived Suppressor CellsGastrointestinal MicrobiomeTumor BurdenMice, Inbred C57BLReceptors, EstrogenDisease ProgressionFemaleImmunotherapySpleen

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good health