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Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs

Cell Reports(2021)10.1016/j.celrep.2021.109372Source: DataRank Database

Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 21 times.

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Open Access21 citations

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Enrichment:Funding (18 grants)Impact (FWCI 1.47)OA: goldTopics (79)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Cristina Lebrero‐Fernández ORCID,Alba Sanz,Nerea Deleyto-Seldas ORCID,Ana Belén Plata-Gómez ORCID,Camino Menéndez ORCID

Live enrichment

PubMed:34260908 PMC:PMC8355512 OpenAlex:https://openalex.org/W3183105421

Instituto de Salud Carlos III

Grant: MS16/00112

Instituto de Salud Carlos III

Grant: PI18/00816

European Regional Development Fund

Grant: SAF2015-67538-R

European Regional Development Fund

Grant: PID2019-104012RB-I00

H2020

Grant: ERC-2014-STG-638891

España Ministerio de Ciencia Innovación y Universidades

Grant: RYC-2013-13546

España Ministerio de Ciencia Innovación y Universidades

Grant: SAF2016-81975-REDT

Agencia Estatal de Investigación

Grant: AEI/10.13039/501100011033

NIH

Grant: R37 AI047389

NIH

Grant: R01 CA103866

NIH

Grant: R01 CA129105

NIAID NIH HHS

Grant: R01 AI047389

European Research Council

Grant: 638891

The Physiology of Nutrient Sensing by mTOR

NHGRI NIH HHS

Grant: RM1 HG009490

National Institutes of Health

Grant: 2R01CA129105-06

Cell Growth Signaling in Cancer Development

National Institutes of Health

Grant: 5R37AI047389-20

Novel Components of the mTORC1 and mTORC2 Pathways

National Institutes of Health

Grant: 5R01CA103866-18

Regulation of the mTOR Pathway by Nutrients

EMBO

FWCI

1.47

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S2211124721007701/pdf

publisherhttp://www.cell.com/article/S2211124721007701/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721007701?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721007701?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2021.109372

Fields of Study

T-cell and B-cell ImmunologyPI3K/AKT/mTOR signaling in cancerImmune Cell Function and Interaction0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsB-LymphocytesCarcinogenesisFemaleGene Knock-In TechniquesHeterozygoteImmunity, HumoralLongevityLymphomaMaleMechanistic Target of Rapamycin Complex 1Mice, Mutant StrainsMonomeric GTP-Binding ProteinsMutationSignal TransductionMice

MeSH Terms

Mechanistic Target of Rapamycin Complex 1AnimalsB-LymphocytesFemaleHeterozygoteLongevityLymphomaMaleMice, Mutant StrainsMutationSignal TransductionMonomeric GTP-Binding ProteinsMiceGene Knock-In TechniquesImmunity, HumoralCarcinogenesis

Keywords

BiologyGTPasePhenotypeCell biologySignal transductionCancer researchSmall GTPaseAutoimmunityCellCell signalingImmunologyGeneImmune systemGeneticsAgingLongevityLymphocytesCell growthB cell lymphomaMtorGerminal CenterNutrient SignalingRag GtpaseRragcMaleHeterozygoteLymphomaQH301-705.5CarcinogenesisMechanistic Target of Rapamycin Complex 1ArticleMiceAnimalsGene Knock-In TechniquesBiology (General)Monomeric GTP-Binding ProteinsB-LymphocytesMice, Mutant StrainsImmunity, HumoralMutationFemale

Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs

FAIR Checklist

Authors (9)

Funding (18 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)