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Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes

Cell Reports(2021)10.1016/j.celrep.2021.109490Source: DataRank Database

Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 30 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access30 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 4.66)OA: goldTopics (72)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (4)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (22)

Karthika Annamalai ORCID,Hazem Ibrahim ORCID,Supreet Kaur ORCID,Shirin Geravandi ORCID,Bhavishya Sarma ORCID

Live enrichment

PubMed:34348155 PMC:PMC8421018 OpenAlex:https://openalex.org/W3190127525

JDRF

Grant: 31-2008-413

NIH

Grant: 2UC4DK098085

NIDDK NIH HHS

Grant: UC4 DK098085

National Institutes of Health

Grant: 1UC4DK098085-01

The Human Islet Distribution Coordinating Center (UC4)

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

University of California, San Diego

National Institute of Diabetes and Digestive and Kidney Diseases

Universität Bremen

Cornell University

DFG

FWCI

4.66

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S2211124721009177/pdf

publisherhttp://www.cell.com/article/S2211124721009177/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721009177?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721009177?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2021.109490

Fields of Study

Pancreatic function and diabetesMetabolism, Diabetes, and CancerDiabetes and associated disorders0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

Mechanistic Target of Rapamycin Complex 1Insulin SecretionAnimalsCell SurvivalDiabetes Mellitus, Type 2FemaleHumansMaleModels, BiologicalNuclear ProteinsPhosphoprotein PhosphatasesProto-Oncogene ProteinsStress, PhysiologicalProtein BiosynthesisSignal TransductionUp-RegulationApoptosisHepatocyte Growth FactorGene DeletionMice, KnockoutInsulin-Secreting CellsProto-Oncogene Proteins c-aktMiceDiet, High-Fat

Keywords

Diabetes mellitusPhosphataseChemistryInternal medicineEndocrinologyPhosphorylationCell biologyBiochemistryBiologyMedicineApoptosisInsulinType 2 diabetesBeta cellAKTMtorc1T2dMst1Phlpp1/2Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatases 1 And 2Male570Cell Survival610Mechanistic Target of Rapamycin Complex 1Diet, High-FatModels, BiologicalArticleInsulin-Secreting CellsProto-Oncogene ProteinsInsulin SecretionPhosphoprotein PhosphatasesAnimalsHumansMice, KnockoutHepatocyte Growth FactorNuclear ProteinsDiabetes Mellitus, Type 2Protein BiosynthesisFemaleProto-Oncogene Proteins c-aktGene Deletion

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good healthSDG 12: 12. Responsible consumptionSDG 0: Good health and well-being