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PBRM1 loss in kidney cancer unbalances the proximal tubule master transcription factor hub to repress proximal tubule differentiation

Cell Reports(2021)10.1016/j.celrep.2021.109747Source: DataRank Database

PBRM1 loss in kidney cancer unbalances the proximal tubule master transcription factor hub to repress proximal tubule differentiation is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 22 times.

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Enrichment:Funding (13 grants)OA: goldTopics (77)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Francis Enane ORCID,Rita Tohmé ORCID,Caroline Schuerger ORCID,Tomas Radivoyevitch ORCID,Yvonne Parker ORCID

Live enrichment

PubMed:34551289 PMC:PMC8561673

National Heart, Lung, and Blood Institute

Grant: PO1 HL146372

National Cancer Institute

Grant: P30 CA043703

National Cancer Institute

Grant: RO1 CA204373

NHLBI NIH HHS

Grant: P01 HL146372

NHLBI NIH HHS

Grant: U01 HL117658

NCI NIH HHS

Grant: R01 CA138858

NCI NIH HHS

Grant: R01 CA204373

NIAID NIH HHS

Grant: R21 AI163656

NIH HHS

Grant: S10 OD023436

NHLBI NIH HHS

Grant: R44 HL135896

National Institutes of Health

Grant: 3P30CA043703-20S1

Case Comprehensive Cancer Center Support Grant

National Institutes of Health

Grant: 1R01CA204373-01

Imaging Liver Cancer Proliferation

National Institutes of Health

Grant: 5P01HL146372-04

Targeting Enzymatic Regulation of Fetal Hemoglobin Repression

goldLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.celrep.2021.109747

publisherhttps://api.elsevier.com/content/article/PII:S2211124721012018?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721012018?httpAccept=text/plain

repositoryhttps://scholarworks.iupui.edu/bitstreams/6e9cdc18-f959-4db8-8ead-60be6f190de4/download

repositoryhttps://doaj.org/article/f98e1e6e3d8849b89d2452aa8f85efa1

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsCarcinoma, Renal CellCell DifferentiationCell Line, TumorCell ProliferationDNA-Binding ProteinsHistonesHumansKidney NeoplasmsKidney Tubules, ProximalMaleMiceMice, NudeMutagenesisPAX8 Transcription FactorProtein Interaction MapsRNA InterferenceRNA, Small InterferingTranscription FactorsTranscriptional ActivationTransplantation, Heterologous

MeSH Terms

Kidney Tubules, ProximalCell Line, TumorAnimalsHumansMiceMice, NudeCarcinoma, Renal CellKidney NeoplasmsDNA-Binding ProteinsHistonesTranscription FactorsRNA, Small InterferingTransplantation, HeterologousCell DifferentiationCell ProliferationRNA InterferenceMutagenesisMaleTranscriptional ActivationProtein Interaction MapsPAX8 Transcription Factor

Keywords

CorepressorMYCcoactivatorRenal cell cancerEpithelial DifferentiationPax8Pbrm1Master Transcription FactorNephric LineageMaleTranscriptional ActivationQH301-705.5Mice, NudeArticleHistonesKidney Tubules, ProximalMicePAX8 Transcription FactorCell Line, TumorAnimalsHumansProtein Interaction MapsBiology (General)RNA, Small InterferingCarcinoma, Renal CellCell ProliferationCell DifferentiationKidney NeoplasmsDNA-Binding ProteinsMutagenesisRNA InterferenceTranscription Factors

Sustainable Development Goals

SDG 3: 3. Good health

PBRM1 loss in kidney cancer unbalances the proximal tubule master transcription factor hub to repress proximal tubule differentiation

FAIR Checklist

Authors (12)

Funding (13 grants)

Open Access

Topics

Annotations (Europe PMC)