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mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits

Cell Reports(2021)10.1016/j.celrep.2021.109950Source: DataRank Database

mGlu1 potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 41 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access41 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (27 grants)OA: goldTopics (86)IDs (PubMed)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Nellie Byun,Deborah J. Luessen ORCID,Brianna Li,Robert Barry ORCID,John C. Gore ORCID

Live enrichment

PubMed:34731619

Canadian Institutes of Health Research

Grant: DFS146189

Canadian Institutes of Health Research

Grant: K99AA027806

National Institutes of Health

Grant: R01MH119673

National Institutes of Health

Grant: R37NS031373

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: DK20593

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: EY08126

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: CA68485

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: DK58404

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: U54HD083211

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: DK59637

National Institutes of Health

Grant: 5P60DK020593-25

Diabetes Research and Training Center

National Institutes of Health

Grant: 3P30CA068485-23S2

Cancer Center Support Grant

National Institutes of Health

Grant: 5U54HD083211-03

Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at Vanderbilt University

National Institutes of Health

Grant: 1U24DK059637-01

CORE--METABOLIC PATHOPHYSIOLOGY

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5K99AA027806-02

Sex differences in fast-spiking interneurons promote AUD-related PFC dysfunction: remediation by modulating mGlu1 and mGlu5

National Institutes of Health

Grant: 5R01MH119673-04

Discovery of mGlu receptor PAMs for treatment of schizophrenia

National Institutes of Health

Grant: 5R37NS031373-22

Functions of Metabotropic Glutamate Receptor Subtypes

National Institutes of Health

Grant: 1P30DK058404-01A1

CORE--MICROARRAY

NINDS NIH HHS

Grant: R01 NS031373

NEI NIH HHS

Grant: P30 EY008126

NIDDK NIH HHS

Grant: P30 DK020593

NCI NIH HHS

Grant: P30 CA068485

NICHD NIH HHS

Grant: P50 HD103537

NIDDK NIH HHS

Grant: U24 DK059637

NIDDK NIH HHS

Grant: P30 DK058404

NIMH NIH HHS

Grant: T32 MH065215

goldLicense: cc-by

publisherhttp://www.cell.com/article/S2211124721014273/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721014273?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721014273?httpAccept=text/plain

repositoryhttps://doaj.org/article/a075ccbe92734d68bafa119211f41b75

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8628371

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsAntipsychotic AgentsBehavior, AnimalCognitionCognitive DysfunctionDisease Models, AnimalExcitatory Amino Acid AgonistsFemaleGABAergic NeuronsGlycineInterneuronsMaleMemory, Short-TermMice, Inbred C57BLMice, TransgenicNeural InhibitionPrefrontal CortexRats, Sprague-DawleyReceptors, Metabotropic GlutamateResorcinolsSchizophreniaSchizophrenic PsychologySomatostatinMiceRats

MeSH Terms

AnimalsAntipsychotic AgentsBehavior, AnimalCognitionCognitive DysfunctionDisease Models, AnimalExcitatory Amino Acid AgonistsFemaleGABAergic NeuronsGlycineInterneuronsMaleMemory, Short-TermMice, Inbred C57BLMice, TransgenicNeural InhibitionPrefrontal CortexRats, Sprague-DawleyReceptors, Metabotropic GlutamateResorcinolsSchizophreniaSchizophrenic PsychologySomatostatinMiceRats

Keywords

MaleQH301-705.5GlycinePrefrontal CortexMice, TransgenicReceptors, Metabotropic GlutamateArticleRats, Sprague-DawleyCognitionInterneuronsexcitation-inhibition balanceExcitatory Amino Acid AgonistsAnimalsCognitive Dysfunctionmetabotropic glutamate receptorBiology (General)GABAergic Neuronssomatostatin interneuronsBehavior, AnimalNeural InhibitionResorcinolsinhibitory transmissionMice, Inbred C57BLDisease Models, AnimalMemory, Short-TermmGlu1FemaleAntipsychotic AgentsNMDA receptor hypofunctioncognitive deficitsmGlu(1)schizophreniaworking memory

Sustainable Development Goals

SDG 3: 3. Good health