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A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors

Cell Reports(2021)10.1016/j.celrep.2021.109953Source: DataRank Database

A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 9 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access9 citations

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cellosaurus pdb

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.37)OA: goldTopics (41)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Tanmoy Mondal ORCID,Evan Lyerly,Sanchita Bhatnagar ORCID,Charles N. Landen ORCID,Shivani Reddy ORCID

Live enrichment

PubMed:34731630 PMC:PMC8720280 OpenAlex:https://openalex.org/W3209600971

National Cancer Institute

Grant: R01CA233752

NCI NIH HHS

Grant: P30 CA044579

US Department of Defense

National Institutes of Health

FWCI

0.37

Citation Percentile

0.6%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.cell.com/article/S2211124721014303/pdf

publisherhttp://www.cell.com/article/S2211124721014303/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721014303?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721014303?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2021.109953

Fields of Study

Cell death mechanisms and regulationRNA Interference and Gene DeliveryRadiopharmaceutical Chemistry and Applications

MeSH Terms

A549 CellsAntineoplastic Agents, ImmunologicalAnimalsAntibodies, MonoclonalAntibody SpecificityEpitopesHumansMice, Inbred C57BLNeoplasmsSignal TransductionMice, SCIDMice, Inbred NODApoptosisXenograft Model Antitumor AssaysTumor BurdenMiceReceptors, TNF-Related Apoptosis-Inducing LigandAntibodies, Monoclonal, Humanized

Keywords

EctodomainAntibodyReceptorLigand (biochemistry)Cancer researchFunction (biology)ApoptosisBlockadeChemistryCell biologyBiologyImmunologyBiochemistryDeath receptorSolid TumorsOvarian TumorsReceptor ClusteringTnbcTnf SuperfamilyDeath Receptor Agonist Antibodies

Sustainable Development Goals

SDG 0: Good health and well-being

A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors

FAIR Checklist

Authors (10)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)