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CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling

Cell Reports(2022)10.1016/j.celrep.2021.110009Source: DataRank Database

CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 0. It has been cited 52 times.

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Open Access52 citations

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Enrichment:Funding (10 grants)Impact (FWCI 5.38)OA: goldTopics (75)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Feng Zhang ORCID,Ashley Kuenzi Davis ORCID,Mei Xin ORCID,Gerd Walz ORCID,Weidong Tian ORCID

Live enrichment

PubMed:35021092 PMC:PMC8826493 OpenAlex:https://openalex.org/W4206568576

National Institutes of Health

Grant: P30 DK078392

National Institutes of Health

Grant: R01 AG063967

National Institutes of Health

Grant: R01 CA204895

NHLBI NIH HHS

Grant: R01 HL132211

National Institutes of Health

Grant: 5R01CA204895-04

Leukemia stem cell polarity and differentiation therapy

National Institutes of Health

Grant: 5R01AG063967-04

Novel mechanism of intestinal stem cell aging

National Institutes of Health

Grant: 3P30DK078392-03S1

Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Disease

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

Deutsche Forschungsgemeinschaft

Else Kröner-Fresenius-Stiftung

FWCI

5.38

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S221112472101487X/pdf

publisherhttp://www.cell.com/article/S221112472101487X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S221112472101487X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S221112472101487X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2021.110009

Fields of Study

Hippo pathway signaling and YAP/TAZWnt/β-catenin signaling in development and cancerCancer Cells and Metastasis0301 basic medicine0303 health sciences03 medical and health sciencesAdaptor Proteins, Signal TransducingAnimalsCell DifferentiationCell LineageCell PolarityCell ProliferationEpidermal Growth FactorFemaleHippo Signaling PathwayIntestinesMaleMiceMice, Inbred C57BLSignal TransductionStem CellsTOR Serine-Threonine KinasesWnt Signaling Pathwaycdc42 GTP-Binding Protein

MeSH Terms

Hippo Signaling PathwayAnimalsCell DifferentiationEpidermal Growth FactorFemaleIntestinesMaleMice, Inbred C57BLStem CellsSignal TransductionCell PolarityCell Lineagecdc42 GTP-Binding ProteinAdaptor Proteins, Signal TransducingCell ProliferationMiceTOR Serine-Threonine KinasesWnt Signaling Pathway

Keywords

Cell biologyCell polarityBiologyCDC42PI3K/AKT/mTOR pathwayStem cellHippo signaling pathwayWnt signaling pathwaySignal transductionCellBiochemistryPolarityMouse ModelCell FateMtor SignalingIntestinal Stem CellsHippo SignalingMaleEpidermal Growth FactorStem CellsTOR Serine-Threonine Kinases610Cell DifferentiationArticleIntestinesMice, Inbred C57BLMiceAnimalsCell LineageFemalecdc42 GTP-Binding ProteinAdaptor Proteins, Signal TransducingCell Proliferation

CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling

FAIR Checklist

Authors (7)

Funding (10 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)