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Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes

Cell Reports(2021)10.1016/j.celrep.2021.110136Source: DataRank Database

Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (12 grants)OA: goldTopics (44)IDs (PubMed, PMC)SDGs (1)

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Authors (9)

Aslihan Ambeskovic,Laurel Newman,Jordan Aldersley,Vijaya Balakrishnan,Bradley Smith ORCID

Live enrichment

PubMed:34936873 PMC:PMC8803128

National Cancer Institute

Grant: CA138249

National Cancer Institute

Grant: CA197562

National Human Genome Research Institute

Grant: HG006853

NIEHS NIH HHS

Grant: P30 ES001247

NHGRI NIH HHS

Grant: R00 HG006853

NCI NIH HHS

Grant: R01 CA138249

NHGRI NIH HHS

Grant: K99 HG006853

NCI NIH HHS

Grant: R35 CA197562

National Institutes of Health

Grant: 1K99HG006853-01A1

Statistical Methods for Estimation of Gene Regulatory Networks

National Institutes of Health

Grant: 5R01CA138249-02

Gene Networks Essential to Colon Cancer Phenotype

National Institutes of Health

Grant: 5R35CA197562-05

Mediators of cancer cell homeostasis: intervention targets common to diverse types of cancer

National Institutes of Health

goldLicense: CC BY NC ND

publisherhttp://www.cell.com/article/S2211124721016326/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721016326?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721016326?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8803128

Europe_PMChttps://europepmc.org/articles/PMC8803128

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsHumansMiceNeoplasmsGene Expression ProfilingEpistasis, GeneticGene Expression Regulation, NeoplasticGenotypeMutationGenes, p53OncogenesGenes, rasModels, GeneticFemaleMaleGene Regulatory Networks

Keywords

Cancerp53RasNetwork TopologyGene PerturbationGene Regulatory NetworkOncogene CooperationCooperation Response GenesMaleGenotypeModels, GeneticGene Expression ProfilingEpistasis, GeneticOncogenesGenes, p53ArticleGene Expression Regulation, NeoplasticMiceGenes, rasNeoplasmsMutationAnimalsHumansFemaleGene Regulatory Networks

Sustainable Development Goals

SDG 3: 3. Good health