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SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes

Cell Reports(2021)10.1016/j.celrep.2021.110155Source: DataRank Database

SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 66 times.

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Scored on demand from live citation data

Open Access66 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 3.41)OA: goldTopics (58)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Taewoo Kim ORCID,Jeha Jeon ORCID,Yongwoo Jang ORCID,Patrick B. Kim ORCID,Claúdia Lopes

Live enrichment

PubMed:34965411 PMC:PMC8780843 OpenAlex:https://openalex.org/W4200131257

National Institutes of Health

Grant: NS070577

National Institutes of Health

Grant: OD024622

NIH HHS

Grant: R24 OD024622

NINDS NIH HHS

Grant: R01 NS070577

McLean Hospital

FWCI

3.41

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.celrep.2021.110155

publisherhttps://doi.org/10.1016/j.celrep.2021.110155

publisherhttps://api.elsevier.com/content/article/PII:S221112472101651X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S221112472101651X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34965411

Fields of Study

Mitochondrial Function and PathologyCRISPR and Genetic EngineeringSirtuins and Resveratrol in MedicineAcetylationCellular ReprogrammingDynaminsEnergy MetabolismFibroblastsGlycolysisHumansMAP Kinase Kinase 1MitochondriaMitochondrial DynamicsMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Oxidative PhosphorylationProto-Oncogene Proteins c-aktSirtuin 2

MeSH Terms

AcetylationEnergy MetabolismFibroblastsGlycolysisHumansMitochondriaOxidative PhosphorylationMitogen-Activated Protein Kinase 1DynaminsMitogen-Activated Protein Kinase 3MAP Kinase Kinase 1Proto-Oncogene Proteins c-aktSirtuin 2Mitochondrial DynamicsCellular Reprogramming

Keywords

SIRT2Cell biologyMitochondrial fissionBiologyReprogrammingKinaseMAPK/ERK pathwaySirtuinDownregulation and upregulationPhosphorylationGlycolysisMitochondrionAcetylationBiochemistryMetabolismGeneInduced Pluripotent Stem CellsOxphosAkt1Drp1Metabolic ReprogrammingMitochondrial RemodelingHuman Somatic Cell ReprogrammingWarburg-like EffectMek1-erk Axis

Sustainable Development Goals

SDG 0: Affordable and clean energy

SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes

FAIR Checklist

Authors (9)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)