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Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA

Cell Reports(2022)10.1016/j.celrep.2021.110196Source: DataRank Database

Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 0. It has been cited 81 times.

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Open Access81 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (14 grants)OA: goldTopics (50)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

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Reusable (0/3)

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Authors (7)

Hua Jin ORCID,Xiaojia Huang ORCID,Birendra Chaurasiya ORCID,Daoyin Dong ORCID,Thomas P. Shanley ORCID

Live enrichment

PubMed:34986352 PMC:PMC8769807

National Institutes of Health

Grant: P01HL077806

National Institutes of Health

Grant: R01HL123957

National Institutes of Health

Grant: HL125350

National Institutes of Health

Grant: R01HL133951

National Institutes of Health

Grant: R01HL140409

National Institutes of Health

Grant: R01HL148810

NCATS NIH HHS

Grant: UL1 TR001422

NHLBI NIH HHS

Grant: R01 HL125350

National Institutes of Health

Grant: 7R01HL133951-03

Novel mechanisms of obliterative pulmonary vascular remodeling and sever pulmonary arterial hypertension

National Institutes of Health

Grant: 5R01HL125350-03

Repair mechanisms of sepsis induced endothelial dysfunction and lung injury

National Institutes of Health

Grant: 1P01HL077806-01A1

Core--Physiology Facility

National Institutes of Health

Grant: 5R01HL140409-03

Targeting Smooth Muscle Progenitor Cells for Treatment of Pulmonary Arterial Hypertension

National Institutes of Health

Grant: 7R01HL123957-05

Novel Signalings and Molecular Targets Of Endothelial Regeneration In Aging Lung

National Institutes of Health

Grant: 5R01HL148810-03

Novel mechanisms of endothelial Injury in the pathogenesis of ARDS

goldLicense: cc-by

publisherhttp://www.cell.com/article/S2211124721017009/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721017009?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721017009?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8769807

Europe_PMChttps://europepmc.org/articles/PMC8769807

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Endothelium, VascularCell LineAnimalsMice, Inbred C57BLMice, KnockoutMicePolyethyleneiminePlasmidsFemaleMaleNanoparticlesHigh-Throughput Nucleotide SequencingGenetic TherapyCRISPR-Cas SystemsClustered Regularly Interspaced Short Palindromic RepeatsGene EditingCRISPR-Associated Protein 9RNA, Guide, CRISPR-Cas Systems

Keywords

Gene therapyCardiovascular diseasesNanoparticleLung diseasesGene deliveryEndothelial CellsGenome EditingCrispr-cas9Endothelium TargetingNon-viral Crispr DeliveryGene EditingMaleMice, KnockoutHigh-Throughput Nucleotide SequencingGenetic TherapyRNA, Guide, CRISPR-Cas SystemsArticleCell LineMice, Inbred C57BLMiceCRISPR-Associated Protein 9AnimalsNanoparticlesPolyethyleneimineClustered Regularly Interspaced Short Palindromic RepeatsFemaleEndothelium, VascularCRISPR-Cas SystemsPlasmids

Sustainable Development Goals

SDG 3: 3. Good health