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2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity

Cell Reports(2022)10.1016/j.celrep.2021.110220Source: DataRank Database

2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 0. It has been cited 25 times.

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Open Access25 citations

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Enrichment:Funding (10 grants)OA: goldTopics (45)IDs (PubMed, PMC)Annotations (2)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Maryam Zand ORCID,Li‐Ling Lin ORCID,Meizhen Chen,Anthony Lopez ORCID,Chun-Lin Lin

Live enrichment

PubMed:35021081 PMC:PMC8811753

National Science Foundation

Grant: ABI 1565076

National Science Foundation

Grant: RP170345

NIH

Grant: 1S10OD021805-01

High Throughput DNA Sequencer: Illumina HiSeq 3000 Sequencer

Cancer Prevention and Research Institute of Texas

Grant: RP150600

Cancer Prevention and Research Institute of Texas

Grant: RP160732

National Institutes of Health

Grant: U54 CA217297

National Institutes of Health

Grant: P30 CA054174

NIH HHS

Grant: S10 OD021805

National Institutes of Health

Grant: 5U54CA217297-02

Systems Analysis of Epigenomic Architecture in Cancer Progression

National Institutes of Health

Grant: 5P30CA054174-16

SAN ANTONIO CANCER INSTITUTE

goldLicense: cc-by-nc-nd

publisherhttp://www.cell.com/article/S2211124721017241/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721017241?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721017241?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8811753

Europe_PMChttps://europepmc.org/articles/PMC8811753

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Cell Line, TumorChromatinNucleosomesHumansNeoplasmsGlutaratesAscorbic AcidAlcohol OxidoreductasesIsocitrate DehydrogenaseRepressor ProteinsCell DifferentiationDNA RepairGene ExpressionGene Expression RegulationForkhead Transcription FactorsEpigenome

Keywords

DNA repairBreast cancerOncometabolite2-HydroxyglutarateCancer Cell PlasticityLineage FidelityLuminal-to-basal TransitionChromatin CytofEpigenome FluctuationSingle-cell EpigenomicsGene ExpressionCell DifferentiationForkhead Transcription FactorsAscorbic AcidArticleChromatinIsocitrate DehydrogenaseNucleosomesGlutaratesRepressor ProteinsAlcohol OxidoreductasesEpigenomeGene Expression RegulationCell Line, TumorNeoplasmsHumans

Sustainable Development Goals

SDG 3: 3. Good health

2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity

FAIR Checklist

Authors (12)

Funding (10 grants)

Open Access

Topics

Annotations (Europe PMC)