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Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis

Cell Reports(2022)10.1016/j.celrep.2022.110595Source: DataRank Database

Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 1.7. It has been cited 69 times, with 63 citing works in its 1-hop citation network.

N/A

1.7DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access69 citations · 63 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

ClinicalTrials.govNCT01946165

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 9.12)OA: goldTopics (100)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 36%Citation Network 64%

Base Score Contribution

0.637

From this paper's citation signal

Citation Network Contribution

1.1

From 48 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 63 citers.

Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity
Nature Communications202259 citations62 referencesContributes 0.066
LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function
JCI Insight202343 citations58 referencesContributes 0.065
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment
Cell Death and Disease202510 citations39 referencesContributes 0.061
Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer
Proceedings of the National Academy of Sciences202519 citations54 referencesContributes 0.055
Prostate organoids: emerging experimental tools for translational research
Journal of Clinical Investigation202336 citations67 referencesContributes 0.054

Authors (25)

Yan Wang ORCID,Josué Curto,Sreeharsha Gurrapu ORCID,Sara Laudato,Alekya Rumandla ORCID

Live enrichment

PubMed:35385726 OpenAlex:https://openalex.org/W4223458241

U.S. Department of Defense

Grant: W81XWH-20-1-0217

U.S. Department of Defense

Grant: RP180684

NIH

Grant: P30 CA016672

NIH

Grant: U01 CA224044

NIH

Grant: U54CA224079

NIH

Grant: P30CA008748

NIH

Grant: R35 CA197566

CPRIT

Grant: RR160031

KHIDI

Grant: HI19C0723

National Institutes of Health

Grant: 2P30CA008748-43

MOUSE GENETICS

National Institutes of Health

Grant: 5R35CA197566-04

Mechanisms governing metastatic dormancy and reactivation

National Institutes of Health

Grant: 5U01CA224044-05

Patient-Derived Models of Prostate Cancer for Personalized Medicine

National Institutes of Health

Grant: 3U54CA224079-01S1

The MSKCC-UW/Fred Hutch Prostate Cancer Drug Resistance and Sensitivity Center

National Institutes of Health

Grant: 3P30CA016672-41S4

Cancer Center Support (CORE) Grant

FWCI

9.12

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: CC BY NC ND

journalhttp://www.cell.com/article/S2211124722003436/pdf

publisherhttp://www.cell.com/article/S2211124722003436/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124722003436?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124722003436?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2022.110595

Fields of Study

Prostate Cancer Treatment and ResearchCancer Cells and MetastasisRadiopharmaceutical Chemistry and Applications0301 basic medicine03 medical and health sciencesAnimalsAntineoplastic AgentsBenzamidesCarcinoma, NeuroendocrineCell Line, TumorCell PlasticityDrug Resistance, NeoplasmHumansMaleMiceNeoplastic Stem CellsNitrilesPhenylthiohydantoinProstatic Neoplasms, Castration-ResistantReceptors, AndrogenSignal TransductionTumor Microenvironment

MeSH Terms

Cell PlasticityAnimalsAntineoplastic AgentsBenzamidesHumansMaleNitrilesPhenylthiohydantoinReceptors, AndrogenNeoplastic Stem CellsSignal TransductionCarcinoma, NeuroendocrineDrug Resistance, NeoplasmCell Line, TumorMiceTumor MicroenvironmentProstatic Neoplasms, Castration-Resistant

Keywords

EnzalutamideCancer researchProstate cancerLNCaPMesenchymal stem cellAndrogen receptorBiologyMetastasisCancer stem cellGene silencingStem cellCancerCell biologyGeneticsGeneTumor Microenvironment / drug effectsMaleCell PlasticityDrug ResistanceMiceAndrogen / drug effectsReceptorsTumor MicroenvironmentTP53Biology (General)TumorSignal Transduction*Prostatic Neoplasms, Castration-ResistantNeuroendocrineTumor Microenvironment / physiologyReceptors, AndrogenBenzamidesNeoplastic Stem CellsCell Plasticity / drug effectsCastration-Resistant* / metabolismAndrogen / metabolismCP: CancerSignal TransductionQH301-705.5Neoplastic Stem Cells / drug effectsCell Plasticity / physiologyNeoplastic Stem Cells / metabolism610Antineoplastic AgentsArticleCell LineAntineoplastic Agents* / pharmacologyCell Line, TumorNitrilesPhenylthiohydantoinAnimalsHumansBMP-SMAD signalingCarcinomaProstatic NeoplasmsCarcinoma, NeuroendocrineDrug Resistance, NeoplasmNeoplasmCastration-Resistant* / drug therapyCastration-Resistant* / geneticsandrogen receptor signaling

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being