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The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62

Cell Reports(2022)10.1016/j.celrep.2022.110792Source: DataRank Database

The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62 is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 0. It has been cited 70 times.

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Open Access70 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (18 grants)Impact (FWCI 5.39)OA: goldTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Tania Cid-Diaz,Ángeles Durán ORCID,Marta Osrodek ORCID,Anxo Martínez-Ordóñez ORCID,Miguel Reina‐Campos ORCID

Live enrichment

PubMed:35545049 PMC:PMC9136538 OpenAlex:https://openalex.org/W4280560497

National Institutes of Health

Grant: R01CA246765

National Institutes of Health

Grant: R01CA234245

National Institutes of Health

Grant: R50CA252146

National Institutes of Health

Grant: P50 CA211024

National Institutes of Health

Grant: R01CA265892

National Institutes of Health

Grant: R01CA250025

National Institutes of Health

Grant: R01CA218254

NCI NIH HHS

Grant: P30 CA030199

NCI NIH HHS

Grant: P30 CA014195

NCI NIH HHS

Grant: P30 CA016672

National Institutes of Health

Grant: 5R01CA246765-03

Novel Pathways in the Control of Lineage Plasticity in Neuroendocrine Prostate Cancer

National Institutes of Health

Grant: 5R01CA250025-03

Molecular mechanisms driving mesenchymal colorectal cancer

National Institutes of Health

Grant: 5R01CA234245-02

Non-essential amino acids and sphingolipid diversity in cancer progression

National Institutes of Health

Grant: 1P50CA211024-01A1

Weill Cornell Medicine (WCM) SPORE in Prostate Cancer

National Institutes of Health

Grant: 1R50CA252146-01A1

Identifying and exploiting metabolic vulnerabilities in cancer using mass spectrometry and tracing approaches

National Institutes of Health

Grant: 5R01CA265892-04

Interferon regulation by NBR1-driven chaperone-mediated autophagy in stellate cells in liver cancer

National Institutes of Health

Grant: 1R01CA218254-01

Role of p62 in metabolic reprograming of the tumor stroma in prostate cancer

National Cancer Institute

FWCI

5.39

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.celrep.2022.110792

publisherhttps://doi.org/10.1016/j.celrep.2022.110792

publisherhttps://api.elsevier.com/content/article/PII:S2211124722005599?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124722005599?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35545049

Fields of Study

Cancer-related Molecular PathwaysHistone Deacetylase Inhibitors ResearchMetabolism, Diabetes, and Cancer0301 basic medicine0303 health sciences03 medical and health sciences0302 clinical medicineCancer-Associated FibroblastsFibroblastsLactic AcidNADNeoplasmsPoly(ADP-ribose) Polymerase InhibitorsPoly(ADP-ribose) Polymerases

MeSH Terms

Poly(ADP-ribose) Polymerase InhibitorsCancer-Associated FibroblastsFibroblastsNADNeoplasmsPoly(ADP-ribose) PolymerasesLactic Acid

Keywords

NAD+ kinaseCell biologyChemistryCancer researchBiologyBiochemistryEnzymeStromaAP-1P62Cancer MetabolismParp InhibitorsCancer-associated FibroblastsOlaparibSqstm1Nad(+)/nadhCp: CancerPoly(adp-ribose)-polymerase 1NeoplasmsLactic AcidFibroblastsPoly(ADP-ribose) Polymerase InhibitorsPoly(ADP-ribose) PolymerasesNADArticle

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62

FAIR Checklist

Authors (14)

Funding (18 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)