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A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency

Cell Reports(2022)10.1016/j.celrep.2022.110928Source: DataRank Database

A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 0. It has been cited 25 times.

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Open Access25 citations

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Enrichment:Funding (11 grants)Impact (FWCI 1.41)OA: goldTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Nazym Bashkenova,Yantao Hong,Cong Lyu ORCID,Diana Guallar ORCID,Zhe Hu ORCID

Live enrichment

PubMed:35675764 PMC:PMC9214724 OpenAlex:https://openalex.org/W4281677190

New York State Stem Cell Science

Grant: C35584GG

New York State Stem Cell Science

Grant: 35583GG

NIH

Grant: R01GM129157

NIH

Grant: R01HD097268

NIH

Grant: R01HL146664

NIH

Grant: R01HD095938

National Natural Science Foundation of China

Grant: 31829003

National Institutes of Health

Grant: 7R01GM129157-03

Transcriptional and Epigenetic Control of Pluripotency and Development by Zfp281

National Institutes of Health

Grant: 7R01HD097268-03

Defining Novel Molecular Pathways to Totipotency

National Institutes of Health

Grant: 7R01HL146664-02

TET2-mediated transcriptional and epigenetic control of normal and malignant hematopoiesis

National Institutes of Health

Grant: 5R01HD095938-05

RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells

FWCI

1.41

Citation Percentile

0.8%

Citation Trend

2023

2024

2025

2026

goldLicense: CC BY NC ND

journalhttps://doi.org/10.1016/j.celrep.2022.110928

publisherhttps://doi.org/10.1016/j.celrep.2022.110928

publisherhttps://api.elsevier.com/content/article/PII:S2211124722007100?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124722007100?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35675764

Fields of Study

Epigenetics and DNA MethylationCancer-related gene regulationRNA modifications and cancer0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Cell DifferentiationChromatinPromoter Regions, GeneticDNA MethylationEmbryonic Stem CellsPolycomb Repressive Complex 2

Keywords

PRC2Bivalent chromatinBivalent (engine)ChromatinPolycomb-group proteinsCell biologyEmbryonic stem cellBiologyStem cellGeneChemistryMolecular biologyGeneticsGene expressionRepressorChromatin remodelingEZH2EScRNA-binding proteinsBivalent GenesTet1Neat1Cp: Molecular BiologyCp: Stem Cell ResearchCatalytic Activity IndependentFormative PluripotencyPspc1Pluripotent State TransitionPolycomb Repressive Complex 2Cell DifferentiationDNA MethylationPromoter Regions, GeneticArticleEmbryonic Stem Cells