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Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection

Cell Reports(2022)10.1016/j.celrep.2022.111441Source: DataRank Database

Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 0. It has been cited 12 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

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Enrichment:Funding (3 grants)Impact (FWCI 0.68)OA: goldTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Anju Singh ORCID,Jing Sun ORCID,Makheni Jean Pierre,Lulwah Alsalih,Crystal C. Lipsey ORCID

Live enrichment

PubMed:36179680 PMC:PMC9474420 OpenAlex:https://openalex.org/W4295922573

National Center for Advancing Translational Sciences

National Institutes of Health

National Institute of Allergy and Infectious Diseases

FWCI

0.68

Citation Percentile

0.6%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by-sa

journalhttps://doi.org/10.1016/j.celrep.2022.111441

publisherhttps://doi.org/10.1016/j.celrep.2022.111441

publisherhttps://api.elsevier.com/content/article/PII:S2211124722012827?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124722012827?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36179680

Fields of Study

Immune responses and vaccinationsImmune Cell Function and InteractionImmune cells in cancerCytokinesHumansIndole AlkaloidsLipopolysaccharidesMacrophagesQuinazolinonesSARS-CoV-2Syk KinaseTumor Necrosis Factor-alphabeta-GlucansCOVID-19 Drug Treatment

MeSH Terms

Syk KinaseSARS-CoV-2COVID-19 Drug TreatmentHumansLipopolysaccharidesMacrophagesTumor Necrosis Factor-alphaCytokinesIndole Alkaloidsbeta-GlucansQuinazolinones

Keywords

SykLipopolysaccharideTumor necrosis factor alphaRutaecarpineKinaseCytokineBiologyMacrophageCell biologyCytokine stormImmunologyPharmacologyChemistryTyrosine kinaseMedicineSignal transductionBiochemistryIn vitroCoronavirus disease 2019 (COVID-19)Nfat-2Lps ToleranceInnate Immune TrainingSars-cov-2Cp: ImmunologySyk Inhibition

Sustainable Development Goals

SDG 0: Good health and well-being